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216 results

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Page 1
Targeting eIF4G1-dependent translation in melanoma.
Feng Y, Radaeva M, Amiri M, Deshpande AJ, Olson S, Jovanovic P, Pass I, Deng Q, Lazar I, Murad R, Molinolo A, Kim H, Sergienko E, Villaneuva J, Topisirovic I, Jackson M, Sonenberg N, Cherkasov A, Ronai ZA. Feng Y, et al. Among authors: molinolo a. bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.624566. doi: 10.1101/2024.11.20.624566. bioRxiv. 2024. PMID: 39605602 Free PMC article. Preprint.
RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential.
Van Espen B, Oo HZ, Collins C, Fazli L, Molinolo A, Murad R, Gleave M, Ronai ZA. Van Espen B, et al. Among authors: molinolo a. bioRxiv [Preprint]. 2023 Jul 1:2023.06.29.547118. doi: 10.1101/2023.06.29.547118. bioRxiv. 2023. Update in: Mol Cancer Res. 2024 Jan 2;22(1):41-54. doi: 10.1158/1541-7786.MCR-23-0512 PMID: 37425866 Free PMC article. Updated. Preprint.
YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution.
Faraji F, Ramirez SI, Clubb LM, Sato K, Burghi V, Hoang TS, Officer A, Anguiano Quiroz PY, Galloway WMG, Mikulski Z, Medetgul-Ernar K, Marangoni P, Jones KB, Cao Y, Molinolo AA, Kim K, Sakaguchi K, Califano JA 3rd, Smith Q, Goren A, Klein OD, Tamayo P, Gutkind JS. Faraji F, et al. Among authors: molinolo aa. Nat Commun. 2025 Jan 8;16(1):498. doi: 10.1038/s41467-024-55660-6. Nat Commun. 2025. PMID: 39779672 Free PMC article.
Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma.
Zhang Y, Ojalill M, Boyer A, Chen XL, Tahon E, Thivolle Lioux G, Xia M, Abbas M, Soylu HM, Flieder DB, Connolly DC, Molinolo AA, McHale MT, Stupack DG, Schlaepfer DD. Zhang Y, et al. Among authors: molinolo aa. Cancer Res Commun. 2024 Dec 1;4(12):3165-3179. doi: 10.1158/2767-9764.CRC-24-0382. Cancer Res Commun. 2024. PMID: 39585085 Free PMC article.
A genome-wide CRISPR screen reveals that antagonism of glutamine metabolism sensitizes head and neck squamous cell carcinoma to ferroptotic cell death.
Allevato MM, Trinh S, Koshizuka K, Nachmanson D, Nguyen TC, Yokoyama Y, Wu X, Andres A, Wang Z, Watrous J, Molinolo AA, Mali P, Harismendy O, Jain M, Wild R, Gutkind JS. Allevato MM, et al. Among authors: molinolo aa. Cancer Lett. 2024 Aug 28;598:217089. doi: 10.1016/j.canlet.2024.217089. Epub 2024 Jul 2. Cancer Lett. 2024. PMID: 38964731
Correction: a phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic HER2-negative breast cancer.
Shatsky RA, Batra-Sharma H, Helsten T, Schwab RB, Pittman EI, Pu M, Weihe E, Ghia EM, Rassenti LZ, Molinolo A, Cabrera B, Breitmeyer JB, Widhopf Ii GF, Messer K, Jamieson C, Kipps TJ, Parker BA. Shatsky RA, et al. Among authors: molinolo a. Breast Cancer Res. 2024 Mar 13;26(1):46. doi: 10.1186/s13058-024-01805-w. Breast Cancer Res. 2024. PMID: 38481291 Free PMC article. No abstract available.
A phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic Her2-negative breast cancer.
Shatsky RA, Batra-Sharma H, Helsten T, Schwab RB, Pittman EI, Pu M, Weihe E, Ghia EM, Rassenti LZ, Molinolo A, Cabrera B, Breitmeyer JB, Widhopf GF 2nd, Messer K, Jamieson C, Kipps TJ, Parker BA. Shatsky RA, et al. Among authors: molinolo a. Breast Cancer Res. 2024 Feb 26;26(1):32. doi: 10.1186/s13058-024-01782-0. Breast Cancer Res. 2024. PMID: 38408999 Free PMC article. Clinical Trial.
YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution.
Gutkind JS, Faraji F, Ramirez S, Clubb L, Sato K, Quiroz PA, Galloway W, Mikulski Z, Hoang T, Medetgul-Ernar K, Marangoni P, Jones K, Officer A, Molinolo A, Kim K, Sakaguchi K, Califano J, Smith Q, Klein O, Tamayo P. Gutkind JS, et al. Among authors: molinolo a. Res Sq [Preprint]. 2023 Oct 27:rs.3.rs-3426301. doi: 10.21203/rs.3.rs-3426301/v1. Res Sq. 2023. Update in: Nat Commun. 2025 Jan 8;16(1):498. doi: 10.1038/s41467-024-55660-6 PMID: 37961717 Free PMC article. Updated. Preprint.
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. Arang N, et al. Among authors: molinolo aa. Cell Rep Med. 2023 Nov 21;4(11):101244. doi: 10.1016/j.xcrm.2023.101244. Epub 2023 Oct 18. Cell Rep Med. 2023. PMID: 37858338 Free PMC article.
216 results