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The DNA-based Lassa vaccine INO-4500 confers durable protective efficacy in cynomolgus macaques against lethal Lassa fever.
Andrade VM, Cashman K, Rosenke K, Wilkinson E, Josleyn N, Lynn G, Steffens J, Vantongeren S, Wells J, Schmaljohn C, Facemire P, Jiang J, Boyer J, Patel A, Feldmann F, Hanley P, Lovaglio J, White K, Feldmann H, Ramos S, Broderick KE, Humeau LM, Smith TRF. Andrade VM, et al. Among authors: wilkinson e. Commun Med (Lond). 2024 Nov 28;4(1):253. doi: 10.1038/s43856-024-00684-8. Commun Med (Lond). 2024. PMID: 39609515 Free PMC article.
Enhanced Efficacy of a Codon-Optimized DNA Vaccine Encoding the Glycoprotein Precursor Gene of Lassa Virus in a Guinea Pig Disease Model When Delivered by Dermal Electroporation.
Cashman KA, Broderick KE, Wilkinson ER, Shaia CI, Bell TM, Shurtleff AC, Spik KW, Badger CV, Guttieri MC, Sardesai NY, Schmaljohn CS. Cashman KA, et al. Among authors: wilkinson er. Vaccines (Basel). 2013 Jul 18;1(3):262-77. doi: 10.3390/vaccines1030262. Vaccines (Basel). 2013. PMID: 26344112 Free PMC article.
DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs.
Cashman KA, Wilkinson ER, Wollen SE, Shamblin JD, Zelko JM, Bearss JJ, Zeng X, Broderick KE, Schmaljohn CS. Cashman KA, et al. Among authors: wilkinson er. Hum Vaccin Immunother. 2017 Dec 2;13(12):3010-3019. doi: 10.1080/21645515.2017.1382780. Epub 2017 Nov 14. Hum Vaccin Immunother. 2017. PMID: 29135337 Free PMC article.
An atlas of gross and histologic lesions and immunohistochemical immunoreactivity during the temporal progression of aerosolized Lassa virus induced hemorrhagic fever in cynomolgus macaques.
Bohler F, Cashman K, Wilkinson E, Johnson JC, Rosenke K, Shamblin J, Hensley L, Honko A, Shaia C. Bohler F, et al. Among authors: wilkinson e. Front Cell Infect Microbiol. 2024 Feb 9;14:1341891. doi: 10.3389/fcimb.2024.1341891. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38404292 Free PMC article.
Lassa antiviral LHF-535 protects guinea pigs from lethal challenge.
Cashman KA, Wilkinson ER, Posakony J, Madu IG, Tarcha EJ, Lustig KH, Korth MJ, Bedard KM, Amberg SM. Cashman KA, et al. Sci Rep. 2022 Nov 19;12(1):19911. doi: 10.1038/s41598-022-23760-2. Sci Rep. 2022. PMID: 36402782 Free PMC article.
Temporal Progression of Lesions in Guinea Pigs Infected With Lassa Virus.
Bell TM, Shaia CI, Bearss JJ, Mattix ME, Koistinen KA, Honnold SP, Zeng X, Blancett CD, Donnelly GC, Shamblin JD, Wilkinson ER, Cashman KA. Bell TM, et al. Among authors: wilkinson er. Vet Pathol. 2017 May;54(3):549-562. doi: 10.1177/0300985816677153. Epub 2016 Jan 1. Vet Pathol. 2017. PMID: 28438110
869 results