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Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations.
Hołubowicz R, Du SW, Felgner J, Smidak R, Choi EH, Palczewska G, Menezes CR, Dong Z, Gao F, Medani O, Yan AL, Hołubowicz MW, Chen PZ, Bassetto M, Risaliti E, Salom D, Workman JN, Kiser PD, Foik AT, Lyon DC, Newby GA, Liu DR, Felgner PL, Palczewski K. Hołubowicz R, et al. Among authors: foik at. Nat Biomed Eng. 2024 Nov 28. doi: 10.1038/s41551-024-01296-2. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39609561
Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses.
Engfer ZJ, Lewandowski D, Dong Z, Palczewska G, Zhang J, Kordecka K, Płaczkiewicz J, Panas D, Foik AT, Tabaka M, Palczewski K. Engfer ZJ, et al. Among authors: foik at. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2314698120. doi: 10.1073/pnas.2314698120. Epub 2023 Dec 8. Proc Natl Acad Sci U S A. 2023. PMID: 38064509 Free PMC article.
Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision.
Lewandowski D, Foik AT, Smidak R, Choi EH, Zhang J, Hoang T, Tworak A, Suh S, Leinonen H, Dong Z, Pinto AF, Tom E, Luu J, Lee J, Ma X, Bieberich E, Blackshaw S, Saghatelian A, Lyon DC, Skowronska-Krawczyk D, Tabaka M, Palczewski K. Lewandowski D, et al. Among authors: foik at. JCI Insight. 2022 Feb 22;7(4):e156301. doi: 10.1172/jci.insight.156301. JCI Insight. 2022. PMID: 35015730 Free PMC article.
14 results