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Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.
Faliti CE, Mesina M, Choi J, Bélanger S, Marshall MA, Tipton CM, Hicks S, Chappa P, Cardenas MA, Abdel-Hakeem M, Thinnes TC, Cottrell C, Scharer CD, Schief WR, Nemazee D, Woodruff MC, Lindner JM, Sanz I, Crotty S. Faliti CE, et al. Among authors: tipton cm. Immunity. 2024 Dec 10;57(12):2772-2789.e8. doi: 10.1016/j.immuni.2024.11.006. Epub 2024 Nov 28. Immunity. 2024. PMID: 39612915
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
Jenks SA, Cashman KS, Zumaquero E, Marigorta UM, Patel AV, Wang X, Tomar D, Woodruff MC, Simon Z, Bugrovsky R, Blalock EL, Scharer CD, Tipton CM, Wei C, Lim SS, Petri M, Niewold TB, Anolik JH, Gibson G, Lee FE, Boss JM, Lund FE, Sanz I. Jenks SA, et al. Among authors: tipton cm. Immunity. 2018 Oct 16;49(4):725-739.e6. doi: 10.1016/j.immuni.2018.08.015. Epub 2018 Oct 9. Immunity. 2018. PMID: 30314758 Free PMC article.
SLE Antibody-Secreting Cells Are Characterized by Enhanced Peripheral Maturation and Survival Programs.
Chen W, Hong SH, Jenks SA, Anam FA, Tipton CM, Woodruff MC, Hom JR, Cashman KS, Faliti CE, Wang X, Kyu S, Wei C, Scharer CD, Mi T, Hicks S, Hartson L, Nguyen DC, Khosroshahi A, Lee S, Wang Y, Bugrovsky R, Ishii Y, Lee FE, Sanz I. Chen W, et al. Among authors: tipton cm. Res Sq [Preprint]. 2023 Jun 27:rs.3.rs-3016327. doi: 10.21203/rs.3.rs-3016327/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 1;15(1):1899. doi: 10.1038/s41467-024-46053-w PMID: 37461641 Free PMC article. Updated. Preprint.
Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus.
Chen W, Hong SH, Jenks SA, Anam FA, Tipton CM, Woodruff MC, Hom JR, Cashman KS, Faliti CE, Wang X, Kyu S, Wei C, Scharer CD, Mi T, Hicks S, Hartson L, Nguyen DC, Khosroshahi A, Lee S, Wang Y, Bugrovsky R, Ishii Y, Lee FE, Sanz I. Chen W, et al. Among authors: tipton cm. Nat Commun. 2024 Mar 1;15(1):1899. doi: 10.1038/s41467-024-46053-w. Nat Commun. 2024. PMID: 38429276 Free PMC article.
A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans.
Nellore A, Zumaquero E, Scharer CD, Fucile CF, Tipton CM, King RG, Mi T, Mousseau B, Bradley JE, Zhou F, Mutneja S, Goepfert PA, Boss JM, Randall TD, Sanz I, Rosenberg AF, Lund FE. Nellore A, et al. Among authors: tipton cm. Immunity. 2023 Apr 11;56(4):847-863.e8. doi: 10.1016/j.immuni.2023.03.001. Epub 2023 Mar 22. Immunity. 2023. PMID: 36958335 Free PMC article.
Single-cell analysis of human nasal mucosal IgE antibody secreting cells reveals a newly minted phenotype.
Ramonell RP, Brown M, Woodruff MC, Levy JM, Wise SK, DelGaudio J, Duan M, Saney CL, Kyu S, Cashman KS, Hom JR, Fucile CF, Rosenberg AF, Tipton CM, Sanz I, Gibson GC, Lee FE. Ramonell RP, et al. Among authors: tipton cm. Mucosal Immunol. 2023 Jun;16(3):287-301. doi: 10.1016/j.mucimm.2023.02.008. Epub 2023 Mar 15. Mucosal Immunol. 2023. PMID: 36931600 Free PMC article.
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Faliti CE, Van TTP, Anam FA, Cheedarla N, Williams ME, Mishra AK, Usman SY, Woodruff MC, Kraker G, Runnstrom MC, Kyu S, Sanz D, Ahmed H, Ghimire M, Morrison-Porter A, Quehl H, Haddad NS, Chen W, Cheedarla S, Neish AS, Roback JD, Antia R, Hom J, Tipton CM, Lindner JM, Ghosn E, Khurana S, Scharer CD, Khosroshahi A, Lee FE, Sanz I. Faliti CE, et al. Among authors: tipton cm. Nat Immunol. 2025 Jan;26(1):131-145. doi: 10.1038/s41590-024-02010-9. Epub 2024 Nov 12. Nat Immunol. 2025. PMID: 39533072 Free PMC article.
Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Faliti CE, Van TTP, Anam FA, Cheedarla N, Williams ME, Mishra AK, Usman SY, Woodruff MC, Kraker G, Runnstrom MC, Kyu S, Sanz D, Ahmed H, Ghimire M, Morrison-Porter A, Quehl H, Haddad NS, Chen W, Cheedarla S, Neish AS, Roback JD, Antia R, Hom J, Tipton CM, Lindner JM, Ghosn E, Khurana S, Scharer CD, Khosroshahi A, Lee FE, Sanz I. Faliti CE, et al. Among authors: tipton cm. Nat Immunol. 2025 Jan;26(1):148. doi: 10.1038/s41590-024-02045-y. Nat Immunol. 2025. PMID: 39622950 Free PMC article. No abstract available.
194 results