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Page 1
Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32.
Ona Chuquimarca SM, Beenstock J, Daou S, Porat J, Keszei AFA, Yin JZ, Beschauner T, Bayfield MA, Mazhab-Jafari MT, Sicheri F. Ona Chuquimarca SM, et al. Among authors: keszei afa. Nat Commun. 2024 Dec 5;15(1):10633. doi: 10.1038/s41467-024-54787-w. Nat Commun. 2024. PMID: 39639027 Free PMC article.
Unveiling the structural proteome of an Alzheimer's disease rat brain model.
Samani EK, Hasan SMN, Waas M, Keszei AFA, Xu X, Heydari M, Hill ME, McLaurin J, Kislinger T, Mazhab-Jafari MT. Samani EK, et al. Among authors: keszei afa. Structure. 2025 Jan 2;33(1):51-61.e3. doi: 10.1016/j.str.2024.11.004. Epub 2024 Nov 29. Structure. 2025. PMID: 39615488
FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation.
Barbulescu P, Chana CK, Wong MK, Ben Makhlouf I, Bruce JP, Feng Y, Keszei AFA, Wong C, Mohamad-Ramshan R, McGary LC, Kashem MA, Ceccarelli DF, Orlicky S, Fang Y, Kuang H, Mazhab-Jafari M, Pezo RC, Bhagwat AS, Pugh TJ, Gingras AC, Sicheri F, Martin A. Barbulescu P, et al. Among authors: keszei afa. Nat Commun. 2024 Aug 30;15(1):7541. doi: 10.1038/s41467-024-52009-x. Nat Commun. 2024. PMID: 39215025 Free PMC article.
Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex.
Nguyen DM, Rath DH, Devost D, Pétrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hébert TE, Privé GG. Nguyen DM, et al. Among authors: keszei afa. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2315018121. doi: 10.1073/pnas.2315018121. Epub 2024 Apr 16. Proc Natl Acad Sci U S A. 2024. PMID: 38625940 Free PMC article.
The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA.
Yin JZ, Keszei AFA, Houliston S, Filandr F, Beenstock J, Daou S, Kitaygorodsky J, Schriemer DC, Mazhab-Jafari MT, Gingras AC, Sicheri F. Yin JZ, et al. Among authors: keszei afa. Structure. 2024 Jun 6;32(6):795-811.e6. doi: 10.1016/j.str.2024.02.021. Epub 2024 Mar 25. Structure. 2024. PMID: 38531363
Cryo-EM structure of an active bacterial TIR-STING filament complex.
Morehouse BR, Yip MCJ, Keszei AFA, McNamara-Bordewick NK, Shao S, Kranzusch PJ. Morehouse BR, et al. Among authors: keszei afa. Nature. 2022 Aug;608(7924):803-807. doi: 10.1038/s41586-022-04999-1. Epub 2022 Jul 20. Nature. 2022. PMID: 35859168 Free PMC article.
Structural insights into metazoan pretargeting GET complexes.
Keszei AFA, Yip MCJ, Hsieh TC, Shao S. Keszei AFA, et al. Nat Struct Mol Biol. 2021 Dec;28(12):1029-1037. doi: 10.1038/s41594-021-00690-7. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887561 Free PMC article.
Cyclic CMP and cyclic UMP mediate bacterial immunity against phages.
Tal N, Morehouse BR, Millman A, Stokar-Avihail A, Avraham C, Fedorenko T, Yirmiya E, Herbst E, Brandis A, Mehlman T, Oppenheimer-Shaanan Y, Keszei AFA, Shao S, Amitai G, Kranzusch PJ, Sorek R. Tal N, et al. Among authors: keszei afa. Cell. 2021 Nov 11;184(23):5728-5739.e16. doi: 10.1016/j.cell.2021.09.031. Epub 2021 Oct 12. Cell. 2021. PMID: 34644530 Free PMC article.
19 results