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Page 1
Chemical probes for the identification of the molecular targets of honokiol.
Vázquez-Villa H, Rueda-Zubiaurre A, Fernández D, Foronda R, Parker CG, Cravatt BF, Martín-Fontecha M, Ortega-Gutiérrez S. Vázquez-Villa H, et al. Eur J Med Chem. 2025 Feb 5;283:117102. doi: 10.1016/j.ejmech.2024.117102. Epub 2024 Nov 24. Eur J Med Chem. 2025. PMID: 39616692 Free article.
Cancer-Stem-Cell Phenotype-Guided Discovery of a Microbiota-Inspired Synthetic Compound Targeting NPM1 for Leukemia.
Algar S, Vázquez-Villa H, Aguilar-Garrido P, Navarro-Aguadero MÁ, Velasco-Estévez M, Sánchez-Merino A, Arribas-Álvarez I, Paradela A, Giner-Arroyo RL, Tamargo-Azpilicueta J, Díaz-Moreno I, Martínez-López J, Gallardo M, López-Rodríguez ML, Benhamú B. Algar S, et al. Among authors: vazquez villa h. JACS Au. 2024 Feb 9;4(5):1786-1800. doi: 10.1021/jacsau.3c00682. eCollection 2024 May 27. JACS Au. 2024. PMID: 38818079 Free PMC article.
2-(Fluoromethoxy)-4'-(S-methanesulfonimidoyl)-1,1'-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson's Disease.
García-Cárceles J, Vázquez-Villa H, Brea J, Ladron de Guevara-Miranda D, Cincilla G, Sánchez-Martínez M, Sánchez-Merino A, Algar S, Teresa de Los Frailes M, Roberts RS, Ballesteros JA, Rodríguez de Fonseca F, Benhamú B, Loza MI, López-Rodríguez ML. García-Cárceles J, et al. Among authors: vazquez villa h. J Med Chem. 2022 Sep 22;65(18):12256-12272. doi: 10.1021/acs.jmedchem.2c00949. Epub 2022 Aug 31. J Med Chem. 2022. PMID: 36044544 Free PMC article.
New Trends in Aging Drug Discovery.
Benhamú B, Martín-Fontecha M, Vázquez-Villa H, López-Rodríguez ML, Ortega-Gutiérrez S. Benhamú B, et al. Among authors: vazquez villa h. Biomedicines. 2022 Aug 18;10(8):2006. doi: 10.3390/biomedicines10082006. Biomedicines. 2022. PMID: 36009552 Free PMC article. Review.
Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice.
Khiar-Fernández N, Zian D, Vázquez-Villa H, Martínez RF, Escobar-Peña A, Foronda-Sainz R, Ray M, Puigdomenech-Poch M, Cincilla G, Sánchez-Martínez M, Kihara Y, Chun J, López-Vales R, López-Rodríguez ML, Ortega-Gutiérrez S. Khiar-Fernández N, et al. Among authors: vazquez villa h. J Med Chem. 2022 Aug 25;65(16):10956-10974. doi: 10.1021/acs.jmedchem.2c00046. Epub 2022 Aug 10. J Med Chem. 2022. PMID: 35948083 Free PMC article.
Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity".
Decara JM, Vázquez-Villa H, Brea J, Alonso M, Srivastava RK, Orio L, Alén F, Suárez J, Baixeras E, García-Cárceles J, Escobar-Peña A, Lutz B, Rodríguez R, Codesido E, Garcia-Ladona FJ, Bennett TA, Ballesteros JA, Cruces J, Loza MI, Benhamú B, Rodríguez de Fonseca F, López-Rodríguez ML. Decara JM, et al. Among authors: vazquez villa h. J Med Chem. 2022 Apr 14;65(7):5449-5461. doi: 10.1021/acs.jmedchem.1c01842. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35349261 Free PMC article.
Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
Huecas S, Araújo-Bazán L, Ruiz FM, Ruiz-Ávila LB, Martínez RF, Escobar-Peña A, Artola M, Vázquez-Villa H, Martín-Fontecha M, Fernández-Tornero C, López-Rodríguez ML, Andreu JM. Huecas S, et al. Among authors: vazquez villa h. J Med Chem. 2021 May 13;64(9):5730-5745. doi: 10.1021/acs.jmedchem.0c02207. Epub 2021 Apr 28. J Med Chem. 2021. PMID: 33908781 Free PMC article.
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
González-Gil I, Zian D, Vázquez-Villa H, Hernández-Torres G, Martínez RF, Khiar-Fernández N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Del Valle CR, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, Rodríguez de Fonseca F, Ferrer-Montiel AV, Chun J, López-Vales R, López-Rodríguez ML, Ortega-Gutiérrez S. González-Gil I, et al. Among authors: vazquez villa h. J Med Chem. 2020 Mar 12;63(5):2372-2390. doi: 10.1021/acs.jmedchem.9b01287. Epub 2019 Dec 16. J Med Chem. 2020. PMID: 31790581 Free PMC article.
33 results