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Page 1
Regulatory T cells crosstalk with tumor cells and endothelium through lymphotoxin signaling.
Piao W, Wu L, Xiong Y, Zapas GC, Paluskievicz CM, Oakes RS, Pettit SM, Sleeth ML, Hippen KL, Schmitz J, Ivanyi P, Shetty AC, Song Y, Kong D, Lee Y, Li L, Shirkey MW, Kensiski A, Alvi A, Ho K, Saxena V, Bräsen JH, Jewell CM, Blazar BR, Abdi R, Bromberg JS. Piao W, et al. Among authors: hippen kl. Nat Commun. 2024 Dec 2;15(1):10468. doi: 10.1038/s41467-024-54874-y. Nat Commun. 2024. PMID: 39622857 Free PMC article.
Retinoic acid signaling acts as a rheostat to balance Treg function.
Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, Murphy WJ, Maillard I, Hill GR, Munn DH, Zeiser R, Kean LS, Rathmell JC, Chi H, Noelle RJ, Blazar BR. Thangavelu G, et al. Among authors: hippen kl. Cell Mol Immunol. 2022 Jul;19(7):820-833. doi: 10.1038/s41423-022-00869-y. Epub 2022 May 17. Cell Mol Immunol. 2022. PMID: 35581350 Free PMC article.
PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration.
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, Lape IT, Paluskievicz C, Hippen KL, Lee Y, Silverman E, Shirkey MW, Riella LV, Blazar BR, Bromberg JS. Piao W, et al. Among authors: hippen kl. Nat Commun. 2022 Apr 21;13(1):2176. doi: 10.1038/s41467-022-29930-0. Nat Commun. 2022. PMID: 35449134 Free PMC article.
Regulatory T cells: A review of manufacturing and clinical utility.
Mamo T, Hippen KL, MacMillan ML, Brunstein CG, Miller JS, Wagner JE, Blazar BR, McKenna DH. Mamo T, et al. Among authors: hippen kl. Transfusion. 2022 Apr;62(4):904-915. doi: 10.1111/trf.16797. Epub 2022 Jan 11. Transfusion. 2022. PMID: 35015309 Free PMC article. Review. No abstract available.
Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing.
Knipping F, Newby GA, Eide CR, McElroy AN, Nielsen SC, Smith K, Fang Y, Cornu TI, Costa C, Gutierrez-Guerrero A, Bingea SP, Feser CJ, Steinbeck B, Hippen KL, Blazar BR, McCaffrey A, Mussolino C, Verhoeyen E, Tolar J, Liu DR, Osborn MJ. Knipping F, et al. Among authors: hippen kl. Mol Ther. 2022 Jan 5;30(1):130-144. doi: 10.1016/j.ymthe.2021.10.026. Epub 2021 Nov 2. Mol Ther. 2022. PMID: 34737067 Free PMC article.
Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion.
Hippen KL, Furlan SN, Roychoudhuri R, Wang E, Zhang Y, Osborn MJ, Merkel SC, Hani S, MacMillan ML, Cichocki F, Miller JS, Wagner JE, Restifo NP, Kean LS, Blazar BR. Hippen KL, et al. Cytotherapy. 2021 Aug;23(8):704-714. doi: 10.1016/j.jcyt.2021.02.118. Epub 2021 Apr 20. Cytotherapy. 2021. PMID: 33893050 Free PMC article.
First-in-human phase 1 trial of induced regulatory T cells for graft-versus-host disease prophylaxis in HLA-matched siblings.
MacMillan ML, Hippen KL, McKenna DH, Kadidlo D, Sumstad D, DeFor TE, Brunstein CG, Holtan SG, Miller JS, Warlick ED, Weisdorf DJ, Wagner JE, Blazar BR. MacMillan ML, et al. Among authors: hippen kl. Blood Adv. 2021 Mar 9;5(5):1425-1436. doi: 10.1182/bloodadvances.2020003219. Blood Adv. 2021. PMID: 33666654 Free PMC article. Clinical Trial.
66 results