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Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.
Gorman BR, Voloudakis G, Igo RP Jr, Kinzy T, Halladay CW, Bigdeli TB, Zeng B, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner PA, Zhang W; VA Million Veteran Program; International AMD Genomics Consortium (IAMDGC); Hadi T, Anger MD, Stockwell A, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BL, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Wu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Gorman BR, et al. Among authors: lotery aj. Nat Genet. 2024 Dec;56(12):2659-2671. doi: 10.1038/s41588-024-01764-0. Epub 2024 Dec 2. Nat Genet. 2024. PMID: 39623103
Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma.
Diaz-Torres S, He W, Yu R; IGGC International Glaucoma Genetics Consortium; Khawaja AP, Hammond CJ, Hysi PG, Pasquale LR, Wu Y, Kubo M, Akiyama M, Aung T, Cheng CY, Khor CC, Kraft P, Kang JH, Hewitt AW, Mackey DA, Craig JE, Wiggs JL, Ong JS, MacGregor S, Gharahkhani P. Diaz-Torres S, et al. Nat Commun. 2024 Nov 17;15(1):9959. doi: 10.1038/s41467-024-54301-2. Nat Commun. 2024. PMID: 39551815 Free PMC article.
Metadata-enhanced contrastive learning from retinal optical coherence tomography images.
Holland R, Leingang O, Bogunović H, Riedl S, Fritsche L, Prevost T, Scholl HPN, Schmidt-Erfurth U, Sivaprasad S, Lotery AJ, Rueckert D, Menten MJ; PINNACLE consortium. Holland R, et al. Among authors: lotery aj. Med Image Anal. 2024 Oct;97:103296. doi: 10.1016/j.media.2024.103296. Epub 2024 Aug 10. Med Image Anal. 2024. PMID: 39154616 Free article.
Deep Learning-Based Clustering of OCT Images for Biomarker Discovery in Age-Related Macular Degeneration (PINNACLE Study Report 4).
Holland R, Kaye R, Hagag AM, Leingang O, Taylor TRP, Bogunović H, Schmidt-Erfurth U, Scholl HPN, Rueckert D, Lotery AJ, Sivaprasad S, Menten MJ. Holland R, et al. Among authors: lotery aj. Ophthalmol Sci. 2024 May 31;4(6):100543. doi: 10.1016/j.xops.2024.100543. eCollection 2024 Nov-Dec. Ophthalmol Sci. 2024. PMID: 39139544 Free PMC article.
Comprehensive functional characterization of complement factor I rare variant genotypes identified in the SCOPE geographic atrophy cohort.
Hallam TM, Andreadi A, Sharp SJ, Brocklebank V, Gardenal E, Dreismann A; SCOPE Study Group; Lotery AJ, Marchbank KJ, Harris CL, Jones AV, Kavanagh D. Hallam TM, et al. Among authors: lotery aj. J Biol Chem. 2024 Jul;300(7):107452. doi: 10.1016/j.jbc.2024.107452. Epub 2024 Jun 7. J Biol Chem. 2024. PMID: 38852887 Free PMC article.
276 results