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Page 1
Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages.
Andersson-Rolf A, Groot K, Korving J, Begthel H, Hanegraaf MAJ, VanInsberghe M, Salmén F, van den Brink S, Lopez-Iglesias C, Peters PJ, Krueger D, Beumer J, Geurts MH, Alemany A, Gehart H, Carlotti F, de Koning EJP, Chuva de Sousa Lopes SM, van Oudenaarden A, van Es JH, Clevers H. Andersson-Rolf A, et al. Among authors: van den brink s. Cell. 2024 Dec 26;187(26):7394-7413.e22. doi: 10.1016/j.cell.2024.10.044. Epub 2024 Dec 2. Cell. 2024. PMID: 39626658 Free article.
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Barker N, et al. Among authors: van den born m, van den brink s, van es jh, van de wetering m. Cell Stem Cell. 2010 Jan 8;6(1):25-36. doi: 10.1016/j.stem.2009.11.013. Cell Stem Cell. 2010. PMID: 20085740 Free article.
Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation.
Lin L, DeMartino J, Wang D, van Son GJF, van der Linden R, Begthel H, Korving J, Andersson-Rolf A, van den Brink S, Lopez-Iglesias C, van de Wetering WJ, Balwierz A, Margaritis T, van de Wetering M, Peters PJ, Drost J, van Es JH, Clevers H. Lin L, et al. Among authors: van den brink s. Science. 2023 Oct 27;382(6669):451-458. doi: 10.1126/science.adi2246. Epub 2023 Oct 26. Science. 2023. PMID: 37883554
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
Sato T, Stange DE, Ferrante M, Vries RG, Van Es JH, Van den Brink S, Van Houdt WJ, Pronk A, Van Gorp J, Siersema PD, Clevers H. Sato T, et al. Among authors: van houdt wj, van gorp j, van den brink s, van es jh. Gastroenterology. 2011 Nov;141(5):1762-72. doi: 10.1053/j.gastro.2011.07.050. Epub 2011 Sep 2. Gastroenterology. 2011. PMID: 21889923
Generation of L cells in mouse and human small intestine organoids.
Petersen N, Reimann F, Bartfeld S, Farin HF, Ringnalda FC, Vries RG, van den Brink S, Clevers H, Gribble FM, de Koning EJ. Petersen N, et al. Among authors: van den brink s. Diabetes. 2014 Feb;63(2):410-20. doi: 10.2337/db13-0991. Epub 2013 Oct 15. Diabetes. 2014. PMID: 24130334 Free PMC article.
Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells.
Tüysüz N, van Bloois L, van den Brink S, Begthel H, Verstegen MM, Cruz LJ, Hui L, van der Laan LJ, de Jonge J, Vries R, Braakman E, Mastrobattista E, Cornelissen JJ, Clevers H, Ten Berge D. Tüysüz N, et al. Among authors: van den brink s, van der laan lj, van bloois l. Nat Commun. 2017 Mar 6;8:14578. doi: 10.1038/ncomms14578. Nat Commun. 2017. PMID: 28262686 Free PMC article.
A new in vitro model for stem cell differentiation and interaction.
Smits AM, van den Hengel LG, van den Brink S, Metz CH, Doevendans PA, Goumans MJ. Smits AM, et al. Among authors: van den hengel lg, van den brink s. Stem Cell Res. 2009 Mar;2(2):108-12. doi: 10.1016/j.scr.2008.10.002. Epub 2008 Nov 11. Stem Cell Res. 2009. PMID: 19383416 Free article.
A functional CFTR assay using primary cystic fibrosis intestinal organoids.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. Dekkers JF, et al. Among authors: van den brink s, van der ent ck. Nat Med. 2013 Jul;19(7):939-45. doi: 10.1038/nm.3201. Epub 2013 Jun 2. Nat Med. 2013. PMID: 23727931
Immunosurveillance against tetraploidization-induced colon tumorigenesis.
Boilève A, Senovilla L, Vitale I, Lissa D, Martins I, Métivier D, van den Brink S, Clevers H, Galluzzi L, Castedo M, Kroemer G. Boilève A, et al. Among authors: van den brink s. Cell Cycle. 2013 Feb 1;12(3):473-9. doi: 10.4161/cc.23369. Epub 2013 Jan 16. Cell Cycle. 2013. PMID: 23324343 Free PMC article.
72 results