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Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing.
Luijten M, van Benthem J, Morita T, Corvi R, Escobar PA, Fujita Y, Hemmerich J, Honarvar N, Kirkland D, Koyama N, Lovell DP, Mathea M, Williams A, Dertinger S, Pfuhler S, Pennings JLA. Luijten M, et al. Among authors: lovell dp. Environ Mol Mutagen. 2024 Dec 3. doi: 10.1002/em.22640. Online ahead of print. Environ Mol Mutagen. 2024. PMID: 39628086
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).
Dertinger SD, Li D, Beevers C, Douglas GR, Heflich RH, Lovell DP, Roberts DJ, Smith R, Uno Y, Williams A, Witt KL, Zeller A, Zhou C. Dertinger SD, et al. Among authors: lovell dp. Environ Mol Mutagen. 2023 Apr 25:10.1002/em.22541. doi: 10.1002/em.22541. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 37097075 Free PMC article. Review.
Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Parsons BL, Beal MA, Dearfield KL, Douglas GR, Gi M, Gollapudi BB, Heflich RH, Horibata K, Kenyon M, Long AS, Lovell DP, Lynch AM, Myers MB, Pfuhler S, Vespa A, Zeller A, Johnson GE, White PA. Parsons BL, et al. Among authors: lovell dp. Environ Mol Mutagen. 2024 Jun 3. doi: 10.1002/em.22599. Online ahead of print. Environ Mol Mutagen. 2024. PMID: 38828778 Review.
Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Beal MA, Chen G, Dearfield KL, Gi M, Gollapudi B, Heflich RH, Horibata K, Long AS, Lovell DP, Parsons BL, Pfuhler S, Wills J, Zeller A, Johnson G, White PA. Beal MA, et al. Among authors: lovell dp. Environ Mol Mutagen. 2023 Dec 19. doi: 10.1002/em.22582. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 38115239 Review.
Evaluating the consistency of judgments derived through both in silico and expert application of the Cramer classification scheme.
Firman JW, Boobis A, Hollnagel HM, Kaiser S, Lovell DP, Moretto A, Mueller S, Rider CV, Schmidt F, Stice S, Wijeyesakere SJ, Borja G, Patlewicz G. Firman JW, et al. Among authors: lovell dp. Food Chem Toxicol. 2024 Dec;194:115070. doi: 10.1016/j.fct.2024.115070. Epub 2024 Oct 22. Food Chem Toxicol. 2024. PMID: 39447833 Free article.
A UK framework for the assessment and integration of different scientific evidence streams in chemical risk assessment.
Doerr B, Botham P, Clare G, Gott D, Gowers A, Guercio V, Gunter Kuhnle, Loizou G, Lovell DP, Pearce N, Rushton L, Toledano M, Wallace HM, Boobis AR. Doerr B, et al. Among authors: lovell dp. Regul Toxicol Pharmacol. 2024 Aug;151:105652. doi: 10.1016/j.yrtph.2024.105652. Epub 2024 Jun 3. Regul Toxicol Pharmacol. 2024. PMID: 38839030 Free article.
A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.
Kirkland D, Whitwell J, Smith R, Hashimoto K, Ji Z, Kenny J, Koyama N, Lovell DP, Martus HJ, Meurer K, Roberts D, Takeiri A, Uno Y, van der Leede BJ, White P, Zeller A. Kirkland D, et al. Among authors: lovell dp. Mutat Res Genet Toxicol Environ Mutagen. 2022 Jul-Aug;879-880:503503. doi: 10.1016/j.mrgentox.2022.503503. Epub 2022 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2022. PMID: 35914859 Free article.
82 results