Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

1,738 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Utilizing an Opportunistic Clinical Study and Population-Based Pharmacokinetic Models to Identify Rational Empiric Dosing Regimens for Piperacillin-Tazobactam in Critically Ill Patients.
Reeder JA, Creech CB, Nation RL, Gu K, Nalbant D, Wu N, Jimenez-Truque N, Fissell W, Rolsma SL, Fishbane N, Kirkpatrick CMJ, Patel PC, Watanabe A, Landersdorfer CB, Winokur P, An G. Reeder JA, et al. Among authors: an g. J Clin Pharmacol. 2024 Dec 3. doi: 10.1002/jcph.6161. Online ahead of print. J Clin Pharmacol. 2024. PMID: 39628093
When considering the minimum inhibitory concentration (MIC) of 16 mg/L for Pseudomonas aeruginosa (a frequently encountered bacterial pathogen among critically ill patients) and a PK/PD target of 100% fT >MIC, continuous infusion of 6 g/day is recommended for critically …
When considering the minimum inhibitory concentration (MIC) of 16 mg/L for Pseudomonas aeruginosa (a frequently encountered bacterial pathog …
Evaluation of Empirical Dosing Regimens for Meropenem in Intensive Care Unit Patients Using Population Pharmacokinetic Modeling and Target Attainment Analysis.
An G, Creech CB, Wu N, Nation RL, Gu K, Nalbant D, Jimenez-Truque N, Fissell W, Rolsma S, Patel PC, Watanabe A, Fishbane N, Kirkpatrick CMJ, Landersdorfer CB, Winokur P. An G, et al. Antimicrob Agents Chemother. 2023 Jan 24;67(1):e0131222. doi: 10.1128/aac.01312-22. Epub 2023 Jan 9. Antimicrob Agents Chemother. 2023. PMID: 36622154 Free PMC article.
Following a daily CI dose of 6 g or higher, more than 30% of the population with a creatinine clearance of <60 mL/min is predicted to have neurotoxicity. With the availability of institution- and/or unit-specific meropenem susceptibility patterns, as well as an i …
Following a daily CI dose of 6 g or higher, more than 30% of the population with a creatinine clearance of <60 mL/min is predicted …
Population pharmacokinetics and target attainment analyses to identify a rational empirical dosing strategy for cefepime in critically ill patients.
An G, Creech CB, Wu N, Nation RL, Gu K, Nalbant D, Jimenez-Truque N, Fissell W, Patel PC, Fishbane N, Watanabe A, Rolsma S, Kirkpatrick CMJ, Landersdorfer CB, Winokur P. An G, et al. J Antimicrob Chemother. 2023 Jun 1;78(6):1460-1470. doi: 10.1093/jac/dkad106. J Antimicrob Chemother. 2023. PMID: 37071586 Free PMC article.
Population Pharmacokinetic Modeling of Cefepime, Meropenem, and Piperacillin-Tazobactam in Patients with Cystic Fibrosis.
Rolsma SL, Sokolow A, Patel PC, Sokolow K, Jimenez-Truque N, Fissell WH, Ryan V, Kirkpatrick CM, Nation RL, Gu K, Teresi M, Fishbane N, Kontos M, An G, Winokur P, Landersdorfer CB, Creech CB. Rolsma SL, et al. Among authors: an g. J Infect Dis. 2024 Sep 30:jiae451. doi: 10.1093/infdis/jiae451. Online ahead of print. J Infect Dis. 2024. PMID: 39344185
Model-Informed Clinical Practice - Determining an Appropriate Ampicillin-Sulbactam Redosing Regimen in Surgical Patients by Utilizing Population Pharmacokinetics and Target Attainment Analysis.
Reeder JA, O'Sullivan CT, Xu M, Wu N, Ince D, Rogers WK, An G. Reeder JA, et al. Among authors: an g. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0124822. doi: 10.1128/aac.01248-22. Epub 2023 Mar 15. Antimicrob Agents Chemother. 2023. PMID: 36920230 Free PMC article.
The final models were two-compartment models for both drugs, with creatinine clearance and heart failure affecting clearance and body surface area having an impact on the central volume of distribution of both ampicillin and sulbactam. Comprehensive Monte Carlo simulations …
The final models were two-compartment models for both drugs, with creatinine clearance and heart failure affecting clearance and body surfac …
Quantification of Cefepime, Meropenem, Piperacillin, and Tazobactam in Human Plasma Using a Sensitive and Robust Liquid Chromatography-Tandem Mass Spectrometry Method, Part 1: Assay Development and Validation.
D'Cunha R, Bach T, Young BA, Li P, Nalbant D, Zhang J, Winokur P, An G. D'Cunha R, et al. Among authors: an g. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e00859-18. doi: 10.1128/AAC.00859-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29941654 Free PMC article.
1,738 results