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Page 1
Population pharmacokinetic analysis of linezolid in low body weight patients with renal dysfunction.
Tsuji Y, Yukawa E, Hiraki Y, Matsumoto K, Mizoguchi A, Morita K, Kamimura H, Karube Y, To H. Tsuji Y, et al. Among authors: to h. J Clin Pharmacol. 2013 Sep;53(9):967-73. doi: 10.1002/jcph.133. J Clin Pharmacol. 2013. PMID: 23918457
Adjustment of the dose of linezolid has been proposed to be unnecessary in patients with reduced renal function. However, platelet counts and hemoglobin levels were shown to be significantly lower in such patients than in patients with normal renal function. ...In t …
Adjustment of the dose of linezolid has been proposed to be unnecessary in patients with reduced renal function. However, platelet co …
Population Pharmacokinetic Approach to the Use of Low Dose Cyclosporine in Patients with Connective Tissue Diseases.
Tsuji Y, Iwanaga N, Mizoguchi A, Sonemoto E, Hiraki Y, Ota Y, Kasai H, Yukawa E, Ueki Y, To H. Tsuji Y, et al. Among authors: to h. Biol Pharm Bull. 2015;38(9):1265-71. doi: 10.1248/bpb.b15-00030. Biol Pharm Bull. 2015. PMID: 26328482 Free article.
A one-compartment open model with absorption was adopted as a pharmacokinetic model, and a nonlinear mixed effects model was used to analyze the population pharmacokinetic models. In the final model, age (AGE) and total body weight (TBW) were influential covariates on clea …
A one-compartment open model with absorption was adopted as a pharmacokinetic model, and a nonlinear mixed effects model was used to …
Pharmacokinetics, toxicity and clinical efficacy of linezolid in Japanese pediatric patients.
Ogami C, Tsuji Y, To H, Yamamoto Y. Ogami C, et al. Among authors: to h. J Infect Chemother. 2019 Dec;25(12):979-986. doi: 10.1016/j.jiac.2019.05.025. Epub 2019 Jun 14. J Infect Chemother. 2019. PMID: 31208925
OBJECTIVES: The aims of the present study were (a) to evaluate the pharmacokinetics of linezolid, and (b) to assess the toxicity and clinical efficacy of linezolid in Japanese pediatric patients. ...Pharmacokinetics of linezolid was assumed to follow one-comp …
OBJECTIVES: The aims of the present study were (a) to evaluate the pharmacokinetics of linezolid, and (b) to assess the toxici …
209 results