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X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes.
Hasenbein TP, Hoelzl S, Smith ZD, Gerhardinger C, Gonner MOC, Aguilar-Pimentel A, Amarie OV, Becker L, Calzada-Wack J, Dragano NRV, da Silva-Buttkus P, Garrett L, Hölter SM, Kraiger M, Östereicher MA, Rathkolb B, Sanz-Moreno A, Spielmann N, Wurst W, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Meissner A, Engelhardt S, Rinn JL, Andergassen D. Hasenbein TP, et al. Among authors: engelhardt s. Nat Commun. 2024 Dec 5;15(1):10631. doi: 10.1038/s41467-024-54673-5. Nat Commun. 2024. PMID: 39638999 Free PMC article.
Development of an intein-mediated split-Cas9 system for gene therapy.
Truong DJ, Kühner K, Kühn R, Werfel S, Engelhardt S, Wurst W, Ortiz O. Truong DJ, et al. Among authors: engelhardt s. Nucleic Acids Res. 2015 Jul 27;43(13):6450-8. doi: 10.1093/nar/gkv601. Epub 2015 Jun 16. Nucleic Acids Res. 2015. PMID: 26082496 Free PMC article.
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.
Sassi Y, Avramopoulos P, Ramanujam D, Grüter L, Werfel S, Giosele S, Brunner AD, Esfandyari D, Papadopoulou AS, De Strooper B, Hübner N, Kumarswamy R, Thum T, Yin X, Mayr M, Laggerbauer B, Engelhardt S. Sassi Y, et al. Among authors: engelhardt s. Nat Commun. 2017 Nov 20;8(1):1614. doi: 10.1038/s41467-017-01737-4. Nat Commun. 2017. PMID: 29158499 Free PMC article.
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction.
Trembinski DJ, Bink DI, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo CC, Costa IG, Schürmann C, Leisegang MS, Brandes RP, Alekseeva T, Brill B, Wietelmann A, Johnson CN, Spring-Connell A, Kaulich M, Werfel S, Engelhardt S, Hirt MN, Yorgan K, Eschenhagen T, Kirchhof L, Hofmann P, Jaé N, Wittig I, Hamdani N, Bischof C, Krishnan J, Houtkooper RH, Dimmeler S, Boon RA. Trembinski DJ, et al. Among authors: engelhardt s. Nat Commun. 2020 Apr 27;11(1):2039. doi: 10.1038/s41467-020-15995-2. Nat Commun. 2020. PMID: 32341350 Free PMC article.
Metavinculin modulates force transduction in cell adhesion sites.
Kanoldt V, Kluger C, Barz C, Schweizer AL, Ramanujam D, Windgasse L, Engelhardt S, Chrostek-Grashoff A, Grashoff C. Kanoldt V, et al. Among authors: engelhardt s. Nat Commun. 2020 Dec 17;11(1):6403. doi: 10.1038/s41467-020-20125-z. Nat Commun. 2020. PMID: 33335089 Free PMC article.
MicroRNA-365 regulates human cardiac action potential duration.
Esfandyari D, Idrissou BMG, Hennis K, Avramopoulos P, Dueck A, El-Battrawy I, Grüter L, Meier MA, Näger AC, Ramanujam D, Dorn T, Meitinger T, Hagl C, Milting H, Borggrefe M, Fenske S, Biel M, Dendorfer A, Sassi Y, Moretti A, Engelhardt S. Esfandyari D, et al. Among authors: engelhardt s. Nat Commun. 2022 Jan 11;13(1):220. doi: 10.1038/s41467-021-27856-7. Nat Commun. 2022. PMID: 35017523 Free PMC article.
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.
Beck C, Ramanujam D, Vaccarello P, Widenmeyer F, Feuerherd M, Cheng CC, Bomhard A, Abikeeva T, Schädler J, Sperhake JP, Graw M, Safi S, Hoffmann H, Staab-Weijnitz CA, Rad R, Protzer U, Frischmuth T, Engelhardt S. Beck C, et al. Among authors: engelhardt s. Nat Commun. 2023 Jul 28;14(1):4564. doi: 10.1038/s41467-023-40185-1. Nat Commun. 2023. PMID: 37507393 Free PMC article.
277 results