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Intestinal microbiota-mediated serum pharmacochemistry reveals hepatoprotective metabolites of Platycodonis Radix against APAP-induced liver injury.
Zhong YH, Wu XW, Zhang XY, Zhang SW, Feng Y, Zhang XM, Xu BB, Zhong GY, Huang HL, He JW, Zeng JX, Liang J. Zhong YH, et al. Among authors: zeng jx. J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Jan 15;1251:124395. doi: 10.1016/j.jchromb.2024.124395. Epub 2024 Nov 30. J Chromatogr B Analyt Technol Biomed Life Sci. 2025. PMID: 39644824
The activities and mechanisms of intestinal microbiota metabolites of TCM herbal ingredients could be illustrated by a strategy integrating spectrum-effects, network pharmacology, metabolomics and molecular docking analysis: Platycodin D as an example.
Zhong YH, Liang J, Qin Q, Wang YJ, Peng YM, Zhang T, Liu FY, Zhang XY, He JW, Zhang SW, Zhong GY, Huang HL, Zeng JX. Zhong YH, et al. Among authors: zeng jx. Phytomedicine. 2023 Jul;115:154831. doi: 10.1016/j.phymed.2023.154831. Epub 2023 Apr 17. Phytomedicine. 2023. PMID: 37094423
70 results