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Preclinical safety and efficacy of the recombinant CR1 drug product CSL040 in rats and cynomolgus monkeys.
Ruthsatz T, Wymann S, Velkoska E, Mansour M, Schu D, Lichtfuss M, Rossato P, FitzPatrick M, Hosback S, Dyson A, Herzog E, Martin K, Dietrich B, Hardy MP. Ruthsatz T, et al. Among authors: rossato p. Toxicol Appl Pharmacol. 2024 Dec 6;495:117191. doi: 10.1016/j.taap.2024.117191. Online ahead of print. Toxicol Appl Pharmacol. 2024. PMID: 39647511 Free article.
Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo.
Wymann S, Mischnik M, Leong D, Ghosh S, Tan X, Cao H, Kuehnemuth B, Powers GA, Halder P, de Souza MJ, James HS, Tomasetig V, Lind H, Rossato P, Owczarek CM, Ow SY, Dower SK, Baz Morelli A, Rowe T, Hardy MP. Wymann S, et al. Among authors: rossato p. Biochem J. 2022 May 13;479(9):1007-1030. doi: 10.1042/BCJ20220054. Biochem J. 2022. PMID: 35470373
Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.
Searle AK, Chen YC, Wallert M, McFadyen JD, Maluenda AC, Noonan J, Kanellakis P, Zaldivia MTK, Huang A, Lioe H, Biondo M, Nolte MW, Rossato P, Bobik A, Panousis C, Wang X, Hosseini H, Peter K. Searle AK, et al. Among authors: rossato p. Thromb Haemost. 2022 Feb;122(2):196-207. doi: 10.1055/a-1663-8208. Epub 2022 Jan 21. Thromb Haemost. 2022. PMID: 34619795 Free PMC article.
Treatment with recombinant ADAMTS13, alleviates hypoxia/reoxygenation-induced pathologies in a mouse model of human sickle cell disease.
Rossato P, Glantschnig H, Canneva F, Schuster M, Coulibaly S, Schrenk G, Voelkel D, Dockal M, Plaimauer B, Rottensteiner H, Gritsch H, Federti E, Matte A, De Franceschi L, Scheiflinger F, Hoellriegl W. Rossato P, et al. J Thromb Haemost. 2023 Feb;21(2):269-275. doi: 10.1016/j.jtha.2022.10.016. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36700507 Free article.
Evidence of protective effects of recombinant ADAMTS13 in a humanized model of sickle cell disease.
Rossato P, Federti E, Matte A, Glantschnig H, Canneva F, Schuster M, Coulibaly S, Schrenk G, Voelkel D, Dockal M, Plaimauer B, Andolfo I, Iolascon A, Rottensteiner H, Gritsch H, Scheiflinger F, Hoellriegl W, Franceschi L. Rossato P, et al. Haematologica. 2022 Nov 1;107(11):2650-2660. doi: 10.3324/haematol.2021.280233. Haematologica. 2022. PMID: 35443560 Free PMC article.
Relapse of Anterior Open Bite: A Case Report.
Justulin AF, Rossato PH, Conti AC, Almeida MR, Pedron Oltramari PV, Fernandes TM. Justulin AF, et al. Among authors: rossato ph. Int J Clin Pediatr Dent. 2021 Jan-Feb;14(1):140-144. doi: 10.5005/jp-journals-10005-1893. Int J Clin Pediatr Dent. 2021. PMID: 34326600 Free PMC article.
Clinical complications during early treatment of anterior open bite.
Rossato PH, Bayer LB, Almeida RR, Conti ACCF, Fernandes TMF, Oltramari PVP. Rossato PH, et al. Braz Oral Res. 2021 Jul 5;35:e081. doi: 10.1590/1807-3107bor-2021.vol35.0081. eCollection 2021. Braz Oral Res. 2021. PMID: 34231768 Free article.
28 results