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Enhancing Antibacterial Efficacy: Combining Novel Bacterial Topoisomerase Inhibitors with Efflux Pump Inhibitors and Other Agents Against Gram-Negative Bacteria.
Zorman M, Kokot M, Zdovc I, Senerovic L, Mandic M, Zidar N, Cotman AE, Durcik M, Peterlin Mašič L, Minovski N, Anderluh M, Hrast Rambaher M. Zorman M, et al. Among authors: zidar n. Antibiotics (Basel). 2024 Nov 13;13(11):1081. doi: 10.3390/antibiotics13111081. Antibiotics (Basel). 2024. PMID: 39596774 Free PMC article.
First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo.
Dernovšek J, Urbančič D, Zajec Ž, Sturtzel C, Grissenberger S, Wenninger-Weinzierl A, Gedgaudas M, Zubrienė A, Goričan T, Golič Grdadolnik S, Skok Ž, Ilaš J, Distel M, Zidar N, Tomašič T. Dernovšek J, et al. Among authors: zidar n. Bioorg Chem. 2024 Dec;153:107850. doi: 10.1016/j.bioorg.2024.107850. Epub 2024 Oct 1. Bioorg Chem. 2024. PMID: 39395321 Free article.
Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders.
Dernovšek J, Goričan T, Gedgaudas M, Zajec Ž, Urbančič D, Jug A, Skok Ž, Sturtzel C, Distel M, Grdadolnik SG, Babu K, Panchamatia A, Stachowski TR, Fischer M, Ilaš J, Zubrienė A, Matulis D, Zidar N, Tomašič T. Dernovšek J, et al. Among authors: zidar n. Eur J Med Chem. 2024 Dec 15;280:116934. doi: 10.1016/j.ejmech.2024.116934. Epub 2024 Oct 5. Eur J Med Chem. 2024. PMID: 39388906 Free article.
207 results