Janssen JM - Search Results

1

Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs.

Li Z, Wang X, Janssen JM, Liu J, Tasca F, Hoeben RC, Gonçalves MAFV. Li Z, et al. Among authors: janssen jm. Nucleic Acids Res. 2024 Dec 9:gkae1213. doi: 10.1093/nar/gkae1213. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39657782

2

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

Holkers M, Maggio I, Liu J, Janssen JM, Miselli F, Mussolino C, Recchia A, Cathomen T, Gonçalves MA. Holkers M, et al. Among authors: janssen jm. Nucleic Acids Res. 2013 Mar 1;41(5):e63. doi: 10.1093/nar/gks1446. Epub 2012 Dec 28. Nucleic Acids Res. 2013. PMID: 23275534 Free PMC article.

3

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.

Maggio I, Stefanucci L, Janssen JM, Liu J, Chen X, Mouly V, Gonçalves MA. Maggio I, et al. Among authors: janssen jm. Nucleic Acids Res. 2016 Feb 18;44(3):1449-70. doi: 10.1093/nar/gkv1540. Epub 2016 Jan 13. Nucleic Acids Res. 2016. PMID: 26762977 Free PMC article.

4

Probing the impact of chromatin conformation on genome editing tools.

Chen X, Rinsma M, Janssen JM, Liu J, Maggio I, Gonçalves MA. Chen X, et al. Among authors: janssen jm. Nucleic Acids Res. 2016 Jul 27;44(13):6482-92. doi: 10.1093/nar/gkw524. Epub 2016 Jun 8. Nucleic Acids Res. 2016. PMID: 27280977 Free PMC article.

5

The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies.

Chen X, Liu J, Janssen JM, Gonçalves MAFV. Chen X, et al. Among authors: janssen jm. Mol Ther Nucleic Acids. 2017 Sep 15;8:558-563. doi: 10.1016/j.omtn.2017.08.005. Epub 2017 Aug 12. Mol Ther Nucleic Acids. 2017. PMID: 28918055 Free PMC article. No abstract available.

6

The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events.

Janssen JM, Chen X, Liu J, Gonçalves MAFV. Janssen JM, et al. Mol Ther Nucleic Acids. 2019 Jun 7;16:141-154. doi: 10.1016/j.omtn.2019.02.009. Epub 2019 Feb 20. Mol Ther Nucleic Acids. 2019. PMID: 30884291 Free PMC article.

7

Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.

Chen X, Tasca F, Wang Q, Liu J, Janssen JM, Brescia MD, Bellin M, Szuhai K, Kenrick J, Frock RL, Gonçalves MAFV. Chen X, et al. Among authors: janssen jm. Nucleic Acids Res. 2020 Jan 24;48(2):974-995. doi: 10.1093/nar/gkz1121. Nucleic Acids Res. 2020. PMID: 31799604 Free PMC article.

8

Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components.

Maggio I, Zittersteijn HA, Wang Q, Liu J, Janssen JM, Ojeda IT, van der Maarel SM, Lankester AC, Hoeben RC, Gonçalves MAFV. Maggio I, et al. Among authors: janssen jm. Gene Ther. 2020 May;27(5):209-225. doi: 10.1038/s41434-019-0119-y. Epub 2020 Jan 3. Gene Ther. 2020. PMID: 31900423 Free PMC article.

9

Precise and broad scope genome editing based on high-specificity Cas9 nickases.

Wang Q, Liu J, Janssen JM, Le Bouteiller M, Frock RL, Gonçalves MAFV. Wang Q, et al. Among authors: janssen jm. Nucleic Acids Res. 2021 Jan 25;49(2):1173-1198. doi: 10.1093/nar/gkaa1236. Nucleic Acids Res. 2021. PMID: 33398349 Free PMC article.

10

Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery.

Wang Q, Liu J, Janssen JM, Tasca F, Mei H, Gonçalves MAFV. Wang Q, et al. Among authors: janssen jm. Nucleic Acids Res. 2021 Nov 18;49(20):11986-12001. doi: 10.1093/nar/gkab938. Nucleic Acids Res. 2021. PMID: 34669958 Free PMC article.

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