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NAD+ METABOLISM RESTRICTION BOOSTS HIGH-DOSE MELPHALAN EFFICACY IN PATIENTS WITH MULTIPLE MYELOMA.
Soncini D, Becherini P, Ladisa F, Ravera S, Chedere A, Gelli E, Giorgetti G, Martinuzzi C, Piacente F Dr, Mastracci L, Veneziano C Dr, Santamaria G Dr, Monacelli F, Ghanem MS, Cagnetta A, Guolo F Dr, Garibotto M, Aquino S, Passalacqua M, Bruzzone S, Bellotti A, Duchosal MA, Nahimana AA, Angelucci E, Nagasuma C Prof, Nencioni A, Lemoli RM, Cea M Prof. Soncini D, et al. Among authors: nahimana aa. Blood Adv. 2024 Dec 11:bloodadvances.2024013425. doi: 10.1182/bloodadvances.2024013425. Online ahead of print. Blood Adv. 2024. PMID: 39661983
Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.
Piacente F, Caffa I, Ravera S, Sociali G, Passalacqua M, Vellone VG, Becherini P, Reverberi D, Monacelli F, Ballestrero A, Odetti P, Cagnetta A, Cea M, Nahimana A, Duchosal M, Bruzzone S, Nencioni A. Piacente F, et al. Cancer Res. 2017 Jul 15;77(14):3857-3869. doi: 10.1158/0008-5472.CAN-16-3079. Epub 2017 May 15. Cancer Res. 2017. PMID: 28507103
Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia.
ElMokh O, Matsumoto S, Biniecka P, Bellotti A, Schaeuble K, Piacente F, Gallart-Ayala H, Ivanisevic J, Stamenkovic I, Nencioni A, Nahimana A, Duchosal MA. ElMokh O, et al. Cell Death Dis. 2022 Apr 8;13(4):320. doi: 10.1038/s41419-022-04763-3. Cell Death Dis. 2022. PMID: 35396381 Free PMC article.
26 results