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Glutamine metabolism is essential for coronavirus replication in host cells and in mice.
Greene KS, Choi A, Yang N, Chen M, Li R, Qiu Y, Ezzatpour S, Rojas KS, Shen J, Wilson KF, Katt WP, Aguilar HC, Lukey MJ, Whittaker GR, Cerione RA. Greene KS, et al. Among authors: choi a. J Biol Chem. 2024 Dec 9;301(1):108063. doi: 10.1016/j.jbc.2024.108063. Online ahead of print. J Biol Chem. 2024. PMID: 39662828 Free article.
Inhibiting Glutamine Metabolism Blocks Coronavirus Replication in Mammalian Cells.
Greene KS, Choi A, Chen M, Yang N, Li R, Qiu Y, Lukey MJ, Rojas KS, Shen J, Wilson KF, Katt WP, Whittaker GR, Cerione RA. Greene KS, et al. Among authors: choi a. bioRxiv [Preprint]. 2023 Sep 28:2023.09.27.559756. doi: 10.1101/2023.09.27.559756. bioRxiv. 2023. PMID: 37808692 Free PMC article. Preprint.
Adaptive immune cells are necessary for SARS-CoV-2-induced pathology.
Imbiakha B, Sahler JM, Buchholz DW, Ezzatpour S, Jager M, Choi A, Monreal IA, Byun H, Adeleke RA, Leach J, Whittaker G, Dewhurst S, Rudd BD, Aguilar HC, August A. Imbiakha B, et al. Among authors: choi a. Sci Adv. 2024 Jan 5;10(1):eadg5461. doi: 10.1126/sciadv.adg5461. Epub 2024 Jan 3. Sci Adv. 2024. PMID: 38170764 Free PMC article.
Analysis of the molecular determinants for furin cleavage of the spike protein S1/S2 site in defined strains of the prototype coronavirus murine hepatitis virus (MHV).
Choi A, Kots ED, Singleton DT, Weinstein HA, Whittaker GR. Choi A, et al. bioRxiv [Preprint]. 2023 Jan 12:2023.01.11.523687. doi: 10.1101/2023.01.11.523687. bioRxiv. 2023. Update in: Virus Res. 2024 Feb;340:199283. doi: 10.1016/j.virusres.2023.199283 PMID: 36711446 Free PMC article. Updated. Preprint.
Natural selection differences detected in key protein domains between non-pathogenic and pathogenic Feline Coronavirus phenotypes.
Zehr JD, Pond SLK, Millet JK, Olarte-Castillo XA, Lucaci AG, Shank SD, Ceres KM, Choi A, Whittaker GR, Goodman LB, Stanhope MJ. Zehr JD, et al. Among authors: choi a. bioRxiv [Preprint]. 2023 Jan 11:2023.01.11.523607. doi: 10.1101/2023.01.11.523607. bioRxiv. 2023. Update in: Virus Evol. 2023 Mar 15;9(1):vead019. doi: 10.1093/ve/vead019 PMID: 36712007 Free PMC article. Updated. Preprint.
1,828 results