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Glutamine metabolism is essential for coronavirus replication in host cells and in mice.
Greene KS, Choi A, Yang N, Chen M, Li R, Qiu Y, Ezzatpour S, Rojas KS, Shen J, Wilson KF, Katt WP, Aguilar HC, Lukey MJ, Whittaker GR, Cerione RA. Greene KS, et al. Among authors: shen j. J Biol Chem. 2024 Dec 9;301(1):108063. doi: 10.1016/j.jbc.2024.108063. Online ahead of print. J Biol Chem. 2024. PMID: 39662828 Free article.
Inhibition of the hERG potassium ion channel by different non-nucleoside human cytomegalovirus polymerase antiviral inhibitor series and the exploration of variations on a pyrroloquinoline core to reduce cardiotoxicity potential.
Srinivas Kandadai A, Bai B, Rahim M, Lin F, Gu Z, Qi X, Zhang X, Dong H, Chen Y, Shen J, Nieman JA. Srinivas Kandadai A, et al. Among authors: shen j. Bioorg Med Chem. 2023 May 1;85:117276. doi: 10.1016/j.bmc.2023.117276. Epub 2023 Apr 5. Bioorg Med Chem. 2023. PMID: 37037115
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