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Page 1
Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours.
Melero I, de Miguel Luken M, de Velasco G, Garralda E, Martín-Liberal J, Joerger M, Alonso G, Goebeler ME, Schuler M, König D, Dummer R, Reig M, Rodriguez Ruiz ME, Calvo E, Esteban-Villarrubia J, Oberoi A, Sabat P, Soto-Castillo JJ, Koster KL, Saavedra O, Sayehli C, Gromke T, Läubli H, Ramelyte E, Fortuny M, Landa-Magdalena A, Moreno I, Torres-Jiménez J, Hernando-Calvo A, Hess D, Racca F, Richly H, Schmitt AM, Eggenschwiler C, Sanduzzi-Zamparelli M, Vilalta-Lacarra A, Trojan J, Koch C, Galle PR, Foerster F, Trajanoski Z, Hackl H, Gogolla F, Koll FJ, Wild P, Chun FKH, Reis H, Lloyd P, Machacek M, Gajewski TF, Fridman WH, Eggermont AMM, Bargou R, Schöniger S, Rüschoff J, Tereshchenko A, Zink C, da Silva A, Lichtenegger FS, Akdemir J, Rüdiger M, L'Huillier P, Dutta A, Haake M, Auckenthaler A, Gjorgjioska A, Rössler B, Hermann F, Liebig M, Reichhardt D, Schuberth-Wagner C, Wischhusen J, Fettes P, Auer M, Klar K, Leo E. Melero I, et al. Among authors: hackl h. Nature. 2024 Dec 11. doi: 10.1038/s41586-024-08305-z. Online ahead of print. Nature. 2024. PMID: 39663448
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, Dahlhoff J, Mokhtari F, Kuzkina A, Welters MJP, Benz TM, Sorger L, Thiemann V, Almanzar G, Selle M, Thein K, Späth J, Gonzalez MC, Reitinger C, Ipsen-Escobedo A, Wistuba-Hamprecht K, Eichler K, Filipski K, Zeiner PS, Beschorner R, Goedemans R, Gogolla FH, Hackl H, Rooswinkel RW, Thiem A, Roche PR, Joshi H, Pühringer D, Wöckel A, Diessner JE, Rüdiger M, Leo E, Cheng PF, Levesque MP, Goebeler M, Sauer M, Nimmerjahn F, Schuberth-Wagner C, von Felten S, Mittelbronn M, Mehling M, Beilhack A, van der Burg SH, Riedel A, Weide B, Dummer R, Wischhusen J. Haake M, et al. Among authors: hackl h. Nat Commun. 2023 Jul 20;14(1):4253. doi: 10.1038/s41467-023-39817-3. Nat Commun. 2023. PMID: 37474523 Free PMC article.
The colorectal cancer immune paradox revisited.
Angelova M, Charoentong P, Hackl H, Trajanoski Z. Angelova M, et al. Among authors: hackl h. Oncoimmunology. 2015 Aug 27;5(2):e1078058. doi: 10.1080/2162402X.2015.1078058. eCollection 2016 Feb. Oncoimmunology. 2015. PMID: 27057454 Free PMC article.
Mathematical models for translational and clinical oncology.
Gallasch R, Efremova M, Charoentong P, Hackl H, Trajanoski Z. Gallasch R, et al. Among authors: hackl h. J Clin Bioinforma. 2013 Nov 7;3(1):23. doi: 10.1186/2043-9113-3-23. J Clin Bioinforma. 2013. PMID: 24195863 Free PMC article.
321 results