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CXCL12-targeted immunomodulatory gene therapy reduces radiation-induced fibrosis in healthy tissues.
Paget JT, Ward JA, McKean AR, Mansfield DC, McLaughlin M, Kyula-Currie JN, Smith HG, Roulstone V, Li C, Zhou Y, Hardiman T, Grigoriadis A, O'Brien Coon D, Irshad S, Melcher AA, Harrington KJ, Khan A. Paget JT, et al. Among authors: hardiman t. Mol Cancer Ther. 2024 Dec 12. doi: 10.1158/1535-7163.MCT-23-0872. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39666014
Multiscale deep learning framework captures systemic immune features in lymph nodes predictive of triple negative breast cancer outcome in large-scale studies.
Verghese G, Li M, Liu F, Lohan A, Kurian NC, Meena S, Gazinska P, Shah A, Oozeer A, Chan T, Opdam M, Linn S, Gillett C, Alberts E, Hardiman T, Jones S, Thavaraj S, Jones JL, Salgado R, Pinder SE, Rane S, Sethi A, Grigoriadis A. Verghese G, et al. Among authors: hardiman t. J Pathol. 2023 Aug;260(4):376-389. doi: 10.1002/path.6088. Epub 2023 May 25. J Pathol. 2023. PMID: 37230111 Free PMC article.
TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer.
Beatson RE, Parente-Pereira AC, Halim L, Cozzetto D, Hull C, Whilding LM, Martinez O, Taylor CA, Obajdin J, Luu Hoang KN, Draper B, Iqbal A, Hardiman T, Zabinski T, Man F, de Rosales RTM, Xie J, Aswad F, Achkova D, Joseph CR, Ciprut S, Adami A, Roider HG, Hess-Stumpp H, Győrffy B, Quist J, Grigoriadis A, Sommer A, Tutt ANJ, Davies DM, Maher J. Beatson RE, et al. Among authors: hardiman t. Cell Rep Med. 2021 Dec 21;2(12):100473. doi: 10.1016/j.xcrm.2021.100473. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028614 Free PMC article.
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health.
Tsai PC, Glastonbury CA, Eliot MN, Bollepalli S, Yet I, Castillo-Fernandez JE, Carnero-Montoro E, Hardiman T, Martin TC, Vickers A, Mangino M, Ward K, Pietiläinen KH, Deloukas P, Spector TD, Viñuela A, Loucks EB, Ollikainen M, Kelsey KT, Small KS, Bell JT. Tsai PC, et al. Among authors: hardiman t. Clin Epigenetics. 2018 Oct 20;10(1):126. doi: 10.1186/s13148-018-0558-0. Clin Epigenetics. 2018. PMID: 30342560 Free PMC article.
21 results