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Evaluation of the ASPYRE-Lung targeted variant panel: a rapid, low-input solution for non-small cell lung cancer biomarker testing and experience from three independent sites.
Herlihy SE, Gentile C, Scott SJ, Smith BA, Stoll KA, Schilter KF, Mordaka JM, Palmer RN, Xyrafaki C, Gillon-Zhang E, King C, Evans RT, Green AS, Silva AL, Stolarek-Januszkiewicz M, von Bargen K, Turner I, Ho CH, Collazos A, Potts ND, Nugent D, Jose J, Gray ER, Shapiro E, Levin WJ, Cooke A, Balmforth BW, Osborne RJ, Reddi HV, Van Deerlin VM. Herlihy SE, et al. Among authors: xyrafaki c. Transl Lung Cancer Res. 2024 Nov 30;13(11):3083-3095. doi: 10.21037/tlcr-24-525. Epub 2024 Nov 28. Transl Lung Cancer Res. 2024. PMID: 39670005 Free PMC article.
ASPYRE-Lung: validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in FFPE tissue.
Evans RT, Gillon-Zhang E, Brown JN, Knudsen KE, King C, Green AS, Silva AL, Mordaka JM, Palmer RN, Tomassini A, Collazos A, Xyrafaki C, Turner I, Ho CH, Nugent D, Jose J, Andreazza S, Potts ND, von Bargen K, Gray ER, Stolarek-Januszkiewicz M, Cooke A, Reddi HV, Balmforth BW, Osborne RJ. Evans RT, et al. Among authors: xyrafaki c. Front Oncol. 2024 Sep 25;14:1420162. doi: 10.3389/fonc.2024.1420162. eCollection 2024. Front Oncol. 2024. PMID: 39386190 Free PMC article.
Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE.
Gray ER, Mordaka JM, Christoforou ER, von Bargen K, Potts ND, Xyrafaki C, Silva AL, Stolarek-Januszkiewicz M, Anton K, Powalowska PK, Andreazza S, Tomassini A, Palmer RN, Cooke A, Osborne RJ, Balmforth BW. Gray ER, et al. Among authors: xyrafaki c. BMC Med Genomics. 2022 Oct 12;15(1):215. doi: 10.1186/s12920-022-01363-0. BMC Med Genomics. 2022. PMID: 36224552 Free PMC article.
Single-molecule DNA sequencing of widely varying GC-content using nucleotide release, capture and detection in microdroplets.
Puchtler TJ, Johnson K, Palmer RN, Talbot EL, Ibbotson LA, Powalowska PK, Knox R, Shibahara A, M S Cunha P, Newell OJ, Wu M, Chana J, Athanasopoulou EN, Waeber AM, Stolarek M, Silva AL, Mordaka JM, Haggis-Powell M, Xyrafaki C, Bush J, Topkaya IS, Sosna M, Ingham RJ, Huckvale T, Negrea A, Breiner B, Šlikas J, Kelly DJ, Dunning AJ, Bell NM, Dethlefsen M, Love DM, Dear PH, Kuleshova J, Podd GJ, Isaac TH, Balmforth BW, Frayling CA. Puchtler TJ, et al. Among authors: xyrafaki c. Nucleic Acids Res. 2020 Dec 16;48(22):e132. doi: 10.1093/nar/gkaa987. Nucleic Acids Res. 2020. PMID: 33152076 Free PMC article.