Lerch TF - Search Results

1

Implementing a robust platform analytical procedure for measuring adeno-associated virus vector genome titer.

Powers TW, Sloan CDK, Stano D, Evans B, Liu K, Mariani S, Campbell JA, Lerch TF, Mo JJ. Powers TW, et al. Among authors: lerch tf. Mol Ther Methods Clin Dev. 2024 Nov 15;32(4):101381. doi: 10.1016/j.omtm.2024.101381. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39670179 Free PMC article.

2

Development of an icIEF assay for monitoring AAV capsid proteins and application to gene therapy products.

He XZ, Powers TW, Huang S, Liu Z, Shi H, Orlet JD, Mo JJ, Srinivasan S, Jacobs S, Zhang K, Runnels HA, Anderson MM, Lerch TF. He XZ, et al. Among authors: lerch tf. Mol Ther Methods Clin Dev. 2023 Mar 10;29:133-144. doi: 10.1016/j.omtm.2023.03.002. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 37025949 Free PMC article.

3

Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.

Lerch TF, Sharpe P, Mayclin SJ, Edwards TE, Polleck S, Rouse JC, Zou Q, Conlon HD. Lerch TF, et al. BioDrugs. 2020 Feb;34(1):77-87. doi: 10.1007/s40259-019-00390-1. BioDrugs. 2020. PMID: 31650490 Free PMC article.

4

Oligonucleotide mapping via mass spectrometry to enable comprehensive primary structure characterization of an mRNA vaccine against SARS-CoV-2.

Gau BC, Dawdy AW, Wang HL, Bare B, Castaneda CH, Friese OV, Thompson MS, Lerch TF, Cirelli DJ, Rouse JC. Gau BC, et al. Among authors: lerch tf. Sci Rep. 2023 Jun 3;13(1):9038. doi: 10.1038/s41598-023-36193-2. Sci Rep. 2023. PMID: 37270636 Free PMC article.

5

Infliximab crystal structures reveal insights into self-association.

Lerch TF, Sharpe P, Mayclin SJ, Edwards TE, Lee E, Conlon HD, Polleck S, Rouse JC, Luo Y, Zou Q. Lerch TF, et al. MAbs. 2017 Jul;9(5):874-883. doi: 10.1080/19420862.2017.1320463. Epub 2017 Apr 19. MAbs. 2017. PMID: 28421849 Free PMC article.

6

Characterization of BNT162b2 mRNA to Evaluate Risk of Off-Target Antigen Translation.

Patel HK, Zhang K, Utegg R, Stephens E, Salem S, Welch H, Grobe S, Schlereth J, Kuhn AN, Ryczek J, Cirelli DJ, Lerch TF. Patel HK, et al. Among authors: lerch tf. J Pharm Sci. 2023 May;112(5):1364-1371. doi: 10.1016/j.xphs.2023.01.007. Epub 2023 Jan 13. J Pharm Sci. 2023. PMID: 36642376 Free PMC article.

7

Efficient and Selective Bioconjugation Using Surfactants.

Hu X, Lerch TF, Xu A. Hu X, et al. Among authors: lerch tf. Bioconjug Chem. 2018 Nov 21;29(11):3667-3676. doi: 10.1021/acs.bioconjchem.8b00594. Epub 2018 Oct 23. Bioconjug Chem. 2018. PMID: 30350575

8

The Race to Develop the Pfizer-BioNTech COVID-19 Vaccine: From the Pharmaceutical Scientists' Perspective.

Lewis LM, Badkar AV, Cirelli D, Combs R, Lerch TF. Lewis LM, et al. Among authors: lerch tf. J Pharm Sci. 2023 Mar;112(3):640-647. doi: 10.1016/j.xphs.2022.09.014. Epub 2022 Sep 18. J Pharm Sci. 2023. PMID: 36130677 Free PMC article.

9

Electron microscopy analysis of a disaccharide analog complex reveals receptor interactions of adeno-associated virus.

Xie Q, Spilman M, Meyer NL, Lerch TF, Stagg SM, Chapman MS. Xie Q, et al. Among authors: lerch tf. J Struct Biol. 2013 Nov;184(2):129-35. doi: 10.1016/j.jsb.2013.09.004. Epub 2013 Sep 11. J Struct Biol. 2013. PMID: 24036405 Free PMC article.

10

Characterization of interactions between heparin/glycosaminoglycan and adeno-associated virus.

Zhang F, Aguilera J, Beaudet JM, Xie Q, Lerch TF, Davulcu O, Colón W, Chapman MS, Linhardt RJ. Zhang F, et al. Among authors: lerch tf. Biochemistry. 2013 Sep 10;52(36):6275-85. doi: 10.1021/bi4008676. Epub 2013 Aug 28. Biochemistry. 2013. PMID: 23952613 Free PMC article.

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