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A Putative Frizzled 7-Targeting Compound Acts as a Firefly Luciferase Inhibitor.
Kinsolving J, Grätz L, Voss JH, Löw B, Shorter E, Jude B, Lanner JT, Löber S, Gmeiner P, Schulte G. Kinsolving J, et al. Among authors: voss jh. J Med Chem. 2024 Dec 26;67(24):22332-22341. doi: 10.1021/acs.jmedchem.4c02766. Epub 2024 Dec 13. J Med Chem. 2024. PMID: 39670643 Free PMC article.
Structural basis of frizzled 7 activation and allosteric regulation.
Bous J, Kinsolving J, Grätz L, Scharf MM, Voss JH, Selcuk B, Adebali O, Schulte G. Bous J, et al. Among authors: voss jh. Nat Commun. 2024 Aug 28;15(1):7422. doi: 10.1038/s41467-024-51664-4. Nat Commun. 2024. PMID: 39198452 Free PMC article.
Discovery of Anthranilic Acid Derivatives as Antagonists of the Pro-Inflammatory Orphan G Protein-Coupled Receptor GPR17.
Boshta NM, Lewash M, Köse M, Namasivayam V, Sarkar S, Voss JH, Liedtke AJ, Junker A, Tian M, Stößel A, Rashed M, Mahal A, Merten N, Pegurier C, Hockemeyer J, Kostenis E, Müller CE. Boshta NM, et al. Among authors: voss jh. J Med Chem. 2024 Nov 14;67(21):19365-19394. doi: 10.1021/acs.jmedchem.4c01755. Epub 2024 Nov 1. J Med Chem. 2024. PMID: 39484825
An experimental strategy to probe Gq contribution to signal transduction in living cells.
Patt J, Alenfelder J, Pfeil EM, Voss JH, Merten N, Eryilmaz F, Heycke N, Rick U, Inoue A, Kehraus S, Deupi X, Müller CE, König GM, Crüsemann M, Kostenis E. Patt J, et al. Among authors: voss jh. J Biol Chem. 2021 Jan-Jun;296:100472. doi: 10.1016/j.jbc.2021.100472. Epub 2021 Feb 25. J Biol Chem. 2021. PMID: 33639168 Free PMC article.
Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?
Schlegel JG, Tahoun M, Seidinger A, Voss JH, Kuschak M, Kehraus S, Schneider M, Matthey M, Fleischmann BK, König GM, Wenzel D, Müller CE. Schlegel JG, et al. Among authors: voss jh. ACS Pharmacol Transl Sci. 2021 Feb 19;4(2):888-897. doi: 10.1021/acsptsci.1c00021. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860209 Free PMC article.
29 results