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Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B. Reinecke M, et al. Nat Chem Biol. 2024 May;20(5):577-585. doi: 10.1038/s41589-023-01459-3. Epub 2023 Oct 30. Nat Chem Biol. 2024. PMID: 37904048 Free PMC article.
Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Zecha J, Bayer FP, Wiechmann S, Woortman J, Berner N, Müller J, Schneider A, Kramer K, Abril-Gil M, Hopf T, Reichart L, Chen L, Hansen FM, Lechner S, Samaras P, Eckert S, Lautenbacher L, Reinecke M, Hamood F, Prokofeva P, Vornholz L, Falcomatà C, Dorsch M, Schröder A, Venhuizen A, Wilhelm S, Médard G, Stoehr G, Ruland J, Grüner BM, Saur D, Buchner M, Ruprecht B, Hahne H, The M, Wilhelm M, Kuster B. Zecha J, et al. Among authors: reinecke m. Science. 2023 Apr 7;380(6640):93-101. doi: 10.1126/science.ade3925. Epub 2023 Mar 16. Science. 2023. PMID: 36926954 Free PMC article.
Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor.
Tröster A, DiPrima M, Jores N, Kudlinzki D, Sreeramulu S, Gande SL, Linhard V, Ludig D, Schug A, Saxena K, Reinecke M, Heinzlmeir S, Leisegang MS, Wollenhaupt J, Lennartz F, Weiss MS, Kuster B, Tosato G, Schwalbe H. Tröster A, et al. Among authors: reinecke m. Chemistry. 2023 Apr 21;29(23):e202203967. doi: 10.1002/chem.202203967. Epub 2023 Mar 22. Chemistry. 2023. PMID: 36799129 Free PMC article.
Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.
Němec V, Khirsariya P, Janovská P, Moyano PM, Maier L, Procházková P, Kebková P, Gybel' T, Berger BT, Chaikuad A, Reinecke M, Kuster B, Knapp S, Bryja V, Paruch K. Němec V, et al. Among authors: reinecke m. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202217532. doi: 10.1002/anie.202217532. Epub 2023 Feb 2. Angew Chem Int Ed Engl. 2023. PMID: 36625768
Second primary malignancies induced by radioactive iodine treatment of differentiated thyroid carcinoma - a critical review and evaluation of the existing evidence.
Reinecke MJ, Ahlers G, Burchert A, Eilsberger F, Flux GD, Marlowe RJ, Mueller HH, Reiners C, Rohde F, van Santen HM, Luster M. Reinecke MJ, et al. Eur J Nucl Med Mol Imaging. 2022 Jul;49(9):3247-3256. doi: 10.1007/s00259-022-05762-4. Epub 2022 Mar 23. Eur J Nucl Med Mol Imaging. 2022. PMID: 35320386 Free PMC article. Review.
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.
Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. Stukalov A, et al. Among authors: reinecke m. Nature. 2021 Jun;594(7862):246-252. doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12. Nature. 2021. PMID: 33845483
244 results