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Oxidative conversion of transthyretin in formalin-fixed clinical amyloid samples results in the formation of the His90Asp and His90Asn variants.
Raheja S, Verona G, Florent P, Rendell NB, Nocerino P, Ellemerich S, Fernandes R, Botcher N, Rowczenio D, Gilbertson JA, Simons JP, Gillmore JD, Bellotti V, Taylor GW, Canetti D. Raheja S, et al. Among authors: verona g. Amyloid. 2024 Dec 15:1-8. doi: 10.1080/13506129.2024.2436990. Online ahead of print. Amyloid. 2024. PMID: 39676281
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue.
Canetti D, Rendell NB, Di Vagno L, Gilbertson JA, Rowczenio D, Rezk T, Gillmore JD, Hawkins PN, Verona G, Mangione PP, Giorgetti S, Mauri P, Motta S, De Palma A, Bellotti V, Taylor GW. Canetti D, et al. Among authors: verona g. Amyloid. 2017 Dec;24(4):233-241. doi: 10.1080/13506129.2017.1385452. Epub 2017 Oct 10. Amyloid. 2017. PMID: 29016222
Diagnostic amyloid proteomics: experience of the UK National Amyloidosis Centre.
Canetti D, Rendell NB, Gilbertson JA, Botcher N, Nocerino P, Blanco A, Di Vagno L, Rowczenio D, Verona G, Mangione PP, Bellotti V, Hawkins PN, Gillmore JD, Taylor GW. Canetti D, et al. Among authors: verona g. Clin Chem Lab Med. 2020 Jun 25;58(6):948-957. doi: 10.1515/cclm-2019-1007. Clin Chem Lab Med. 2020. PMID: 32069225 Review.
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils.
Raimondi S, Mangione PP, Verona G, Canetti D, Nocerino P, Marchese L, Piccarducci R, Mondani V, Faravelli G, Taylor GW, Gillmore JD, Corazza A, Pepys MB, Giorgetti S, Bellotti V. Raimondi S, et al. Among authors: verona g. J Biol Chem. 2020 Aug 14;295(33):11379-11387. doi: 10.1074/jbc.RA120.014026. Epub 2020 Jun 22. J Biol Chem. 2020. PMID: 32571879 Free PMC article.
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence.
Canetti D, Nocerino P, Rendell NB, Botcher N, Gilbertson JA, Blanco A, Rowczenio D, Morelli A, Mangione PP, Corazza A, Verona G, Giorgetti S, Marchese L, Westermark P, Hawkins PN, Gillmore JD, Bellotti V, Taylor GW. Canetti D, et al. Among authors: verona g. J Pathol. 2021 Nov;255(3):311-318. doi: 10.1002/path.5770. Epub 2021 Aug 27. J Pathol. 2021. PMID: 34331462 Free PMC article.
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis.
Slamova I, Adib R, Ellmerich S, Golos MR, Gilbertson JA, Botcher N, Canetti D, Taylor GW, Rendell N, Tennent GA, Verona G, Porcari R, Mangione PP, Gillmore JD, Pepys MB, Bellotti V, Hawkins PN, Al-Shawi R, Simons JP. Slamova I, et al. Among authors: verona g. Nat Commun. 2021 Dec 7;12(1):7112. doi: 10.1038/s41467-021-27416-z. Nat Commun. 2021. PMID: 34876572 Free PMC article.
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms.
Faravelli G, Mondani V, Mangione PP, Raimondi S, Marchese L, Lavatelli F, Stoppini M, Corazza A, Canetti D, Verona G, Obici L, Taylor GW, Gillmore JD, Giorgetti S, Bellotti V. Faravelli G, et al. Among authors: verona g. Front Mol Biosci. 2022 Feb 14;9:830006. doi: 10.3389/fmolb.2022.830006. eCollection 2022. Front Mol Biosci. 2022. PMID: 35237660 Free PMC article. Review.
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V. Mangione PP, et al. Among authors: verona g. J Biol Chem. 2018 Sep 14;293(37):14192-14199. doi: 10.1074/jbc.RA118.003990. Epub 2018 Jul 17. J Biol Chem. 2018. PMID: 30018138 Free PMC article.
28 results