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Page 1
Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer's Disease.
Lee D, Vicari JM, Porras C, Spencer C, Pjanic M, Wang X, Kinrot S, Weiler P, Kosoy R, Bendl J, Prashant NM, Psychogyiou K, Malakates P, Hennigan E, Monteiro Fortes J, Zheng S, Therrien K, Mathur D, Kleopoulos SP, Shao Z, Argyriou S, Alvia M, Casey C, Hong A, Beaumont KG, Sebra R, Kellner CP, Bennett DA, Yuan GC, Voloudakis G, Theis FJ, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Lee D, et al. Among authors: hoffman ge. medRxiv [Preprint]. 2024 Dec 5:2023.10.25.23297558. doi: 10.1101/2023.10.25.23297558. medRxiv. 2024. PMID: 39677435 Free PMC article. Preprint.
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.
Humphrey J, Brophy E, Kosoy R, Zeng B, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, Münch A, Kitata RB, Kleopoulos SP, Argyriou S, Shao Z, Francoeur N, Tsai CF, Gritsenko MA, Monroe ME, Paurus VL, Weitz KK, Shi T, Sebra R, Liu T, de Witte LD, Goate AM, Bennett DA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P, Raj T. Humphrey J, et al. Among authors: hoffman ge. medRxiv [Preprint]. 2023 Dec 1:2023.12.01.23299073. doi: 10.1101/2023.12.01.23299073. medRxiv. 2023. PMID: 38076956 Free PMC article. Preprint.
Genetics of the human microglia regulome refines Alzheimer's disease risk loci.
Kosoy R, Fullard JF, Zeng B, Bendl J, Dong P, Rahman S, Kleopoulos SP, Shao Z, Girdhar K, Humphrey J, de Paiva Lopes K, Charney AW, Kopell BH, Raj T, Bennett D, Kellner CP, Haroutunian V, Hoffman GE, Roussos P. Kosoy R, et al. Among authors: hoffman ge. Nat Genet. 2022 Aug;54(8):1145-1154. doi: 10.1038/s41588-022-01149-1. Epub 2022 Aug 5. Nat Genet. 2022. PMID: 35931864 Free PMC article.
Alzheimer's disease transcriptional landscape in ex-vivo human microglia.
Roussos P, Kosoy R, Fullard J, Bendl J, Kleopoulos S, Shao Z, Argyriou S, Mathur D, Vicari J, Ma Y, Humphrey J, Brophy E, Raj T, Katsel P, Voloudakis G, Lee D, Bennett D, Haroutunian V, Hoffman G. Roussos P, et al. Res Sq [Preprint]. 2024 Jan 26:rs.3.rs-3851590. doi: 10.21203/rs.3.rs-3851590/v1. Res Sq. 2024. PMID: 38343831 Free PMC article. Preprint.
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.
Bendl J, Hauberg ME, Girdhar K, Im E, Vicari JM, Rahman S, Fernando MB, Townsley KG, Dong P, Misir R, Kleopoulos SP, Reach SM, Apontes P, Zeng B, Zhang W, Voloudakis G, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Bendl J, et al. Among authors: hoffman ge. Nat Neurosci. 2022 Oct;25(10):1366-1378. doi: 10.1038/s41593-022-01166-7. Epub 2022 Sep 28. Nat Neurosci. 2022. PMID: 36171428 Free PMC article.
IL10RB as a key regulator of COVID-19 host susceptibility and severity.
Voloudakis G, Hoffman G, Venkatesh S, Lee KM, Dobrindt K, Vicari JM, Zhang W, Beckmann ND, Jiang S, Hoagland D, Bian J, Gao L, Corvelo A, Cho K, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Lynch JA, Fullard JF, Roussos P. Voloudakis G, et al. medRxiv [Preprint]. 2021 Jun 2:2021.05.31.21254851. doi: 10.1101/2021.05.31.21254851. medRxiv. 2021. Update in: NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x PMID: 34100031 Free PMC article. Updated. Preprint.
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
Girdhar K, Bendl J, Baumgartner A, Therrien K, Venkatesh S, Mathur D, Dong P, Rahman S, Kleopoulos SP, Misir R, Reach SM, Auluck PK, Marenco S, Lewis DA, Haroutunian V, Funk C, Voloudakis G, Hoffman GE, Fullard JF, Roussos P. Girdhar K, et al. Among authors: hoffman ge. Res Sq [Preprint]. 2023 Oct 2:rs.3.rs-3393581. doi: 10.21203/rs.3.rs-3393581/v1. Res Sq. 2023. PMID: 37886514 Free PMC article. Preprint.
232 results