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Page 1
Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer's Disease.
Lee D, Vicari JM, Porras C, Spencer C, Pjanic M, Wang X, Kinrot S, Weiler P, Kosoy R, Bendl J, Prashant NM, Psychogyiou K, Malakates P, Hennigan E, Monteiro Fortes J, Zheng S, Therrien K, Mathur D, Kleopoulos SP, Shao Z, Argyriou S, Alvia M, Casey C, Hong A, Beaumont KG, Sebra R, Kellner CP, Bennett DA, Yuan GC, Voloudakis G, Theis FJ, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Lee D, et al. Among authors: vicari jm. medRxiv [Preprint]. 2024 Dec 5:2023.10.25.23297558. doi: 10.1101/2023.10.25.23297558. medRxiv. 2024. PMID: 39677435 Free PMC article. Preprint.
Alzheimer's disease transcriptional landscape in ex-vivo human microglia.
Roussos P, Kosoy R, Fullard J, Bendl J, Kleopoulos S, Shao Z, Argyriou S, Mathur D, Vicari J, Ma Y, Humphrey J, Brophy E, Raj T, Katsel P, Voloudakis G, Lee D, Bennett D, Haroutunian V, Hoffman G. Roussos P, et al. Res Sq [Preprint]. 2024 Jan 26:rs.3.rs-3851590. doi: 10.21203/rs.3.rs-3851590/v1. Res Sq. 2024. PMID: 38343831 Free PMC article. Preprint.
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.
Bendl J, Hauberg ME, Girdhar K, Im E, Vicari JM, Rahman S, Fernando MB, Townsley KG, Dong P, Misir R, Kleopoulos SP, Reach SM, Apontes P, Zeng B, Zhang W, Voloudakis G, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Bendl J, et al. Among authors: vicari jm. Nat Neurosci. 2022 Oct;25(10):1366-1378. doi: 10.1038/s41593-022-01166-7. Epub 2022 Sep 28. Nat Neurosci. 2022. PMID: 36171428 Free PMC article.
Multi-omic atlas of the parahippocampal gyrus in Alzheimer's disease.
Coleman C, Wang M, Wang E, Micallef C, Shao Z, Vicari JM, Li Y, Yu K, Cai D, Peng J, Haroutunian V, Fullard JF, Bendl J, Zhang B, Roussos P. Coleman C, et al. Among authors: vicari jm. Sci Data. 2023 Sep 8;10(1):602. doi: 10.1038/s41597-023-02507-2. Sci Data. 2023. PMID: 37684260 Free PMC article.
Multi-omic profiling of the developing human cerebral cortex at the single-cell level.
Zhu K, Bendl J, Rahman S, Vicari JM, Coleman C, Clarence T, Latouche O, Tsankova NM, Li A, Brennand KJ, Lee D, Yuan GC, Fullard JF, Roussos P. Zhu K, et al. Among authors: vicari jm. Sci Adv. 2023 Oct 13;9(41):eadg3754. doi: 10.1126/sciadv.adg3754. Epub 2023 Oct 12. Sci Adv. 2023. PMID: 37824614 Free PMC article.
Population-level variation in enhancer expression identifies disease mechanisms in the human brain.
Dong P, Hoffman GE, Apontes P, Bendl J, Rahman S, Fernando MB, Zeng B, Vicari JM, Zhang W, Girdhar K, Townsley KG, Misir R; CommonMind Consortium; Brennand KJ, Haroutunian V, Voloudakis G, Fullard JF, Roussos P. Dong P, et al. Among authors: vicari jm. Nat Genet. 2022 Oct;54(10):1493-1503. doi: 10.1038/s41588-022-01170-4. Epub 2022 Sep 26. Nat Genet. 2022. PMID: 36163279 Free PMC article.
Novel small molecules inhibit proteotoxicity and inflammation: Mechanistic and therapeutic implications for Alzheimer's Disease, healthspan and lifespan- Aging as a consequence of glycolysis.
Litke R, Vicari J, Huang BT, Shapiro L, Roh KH, Silver A, Talreja P, Palacios N, Yoon Y, Kellner C, Kaniskan H, Vangeti S, Jin J, Ramos-Lopez I, Mobbs C. Litke R, et al. bioRxiv [Preprint]. 2023 Oct 1:2023.06.12.544352. doi: 10.1101/2023.06.12.544352. bioRxiv. 2023. PMID: 37398396 Free PMC article. Preprint.
A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.
Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: vicari jm. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. NPJ Genom Med. 2022. PMID: 36064543 Free PMC article.
11 results