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The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats.
Kodati B, Zhang W, He S, Pham JH, Beall KJ, Swanger ZE, Krishnamoorthy VR, Harris PE, Hall T, Tran AV, Chaphalkar RM, Chavala SH, Stankowska DL, Krishnamoorthy RR. Kodati B, et al. Among authors: chaphalkar rm. Front Ophthalmol (Lausanne). 2023;3:1185755. doi: 10.3389/fopht.2023.1185755. Epub 2023 Jun 16. Front Ophthalmol (Lausanne). 2023. PMID: 38464735 Free PMC article.