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Page 1
Stratified Medicine Paediatrics: Cell free DNA and serial tumour sequencing identifies subtype specific cancer evolution and epigenetic states.
George SL, Lynn C, Stankunaite R, Hughes D, Sauer CM, Chalker J, Waqar Ahmed S, Oostveen M, Proszek PZ, Yuan L, Shaikh R, Jamal S, Brew A, Tall J, Rogers T, Clifford SC, Vormoor J, Shipley JM, Tweddle DA, Jones C, Willis C, Burke GAA, Vedi A, Howell L, Johnston R, Rees H, Adams M, Jesudason A, Ronghe M, Elliott M, Ross E, Makin G, Campbell-Hewson Q, Grundy RG, Turnbull J, Wilson S, Lee V, Gray JC, Stoneham S, Gatz SA, Marshall LV, Angelini P, Anderson J, Cresswell GD, Graham TA, Al-Lazikani B, Cortes-Ciriano I, Kearns P, Hutchinson JC, Hargrave D, Jacques TS, Hubank M, Sottoriva A, Chesler L. George SL, et al. Among authors: graham ta. Cancer Discov. 2024 Dec 19. doi: 10.1158/2159-8290.CD-24-0916. Online ahead of print. Cancer Discov. 2024. PMID: 39693475
Measuring cancer evolution from the genome.
Graham TA, Sottoriva A. Graham TA, et al. J Pathol. 2017 Jan;241(2):183-191. doi: 10.1002/path.4821. Epub 2016 Nov 18. J Pathol. 2017. PMID: 27741350 Review.
Measuring Clonal Evolution in Cancer with Genomics.
Williams MJ, Sottoriva A, Graham TA. Williams MJ, et al. Among authors: graham ta. Annu Rev Genomics Hum Genet. 2019 Aug 31;20:309-329. doi: 10.1146/annurev-genom-083117-021712. Epub 2019 May 5. Annu Rev Genomics Hum Genet. 2019. PMID: 31059289 Review.
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer.
Lakatos E, Gunasri V, Zapata L, Househam J, Heide T, Trahearn N, Swinyard O, Cisneros L, Lynn C, Mossner M, Kimberley C, Spiteri I, Cresswell GD, Llibre-Palomar G, Mitchison M, Maley CC, Jansen M, Rodriguez-Justo M, Bridgewater J, Baker AM, Sottoriva A, Graham TA. Lakatos E, et al. Among authors: graham ta. bioRxiv [Preprint]. 2024 Feb 14:2024.02.12.579956. doi: 10.1101/2024.02.12.579956. bioRxiv. 2024. PMID: 38405882 Free PMC article. Preprint.
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Househam J, Heide T, Cresswell GD, Spiteri I, Kimberley C, Zapata L, Lynn C, James C, Mossner M, Fernandez-Mateos J, Vinceti A, Baker AM, Gabbutt C, Berner A, Schmidt M, Chen B, Lakatos E, Gunasri V, Nichol D, Costa H, Mitchinson M, Ramazzotti D, Werner B, Iorio F, Jansen M, Caravagna G, Barnes CP, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Sottoriva A, Graham TA. Househam J, et al. Among authors: graham ta. Nature. 2022 Nov;611(7937):744-753. doi: 10.1038/s41586-022-05311-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289336 Free PMC article.
Phenotypic noise and plasticity in cancer evolution.
Whiting FJH, Househam J, Baker AM, Sottoriva A, Graham TA. Whiting FJH, et al. Among authors: graham ta. Trends Cell Biol. 2024 Jun;34(6):451-464. doi: 10.1016/j.tcb.2023.10.002. Epub 2023 Nov 15. Trends Cell Biol. 2024. PMID: 37968225 Free article. Review.
Identification of neutral tumor evolution across cancer types.
Williams MJ, Werner B, Barnes CP, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: graham ta. Nat Genet. 2016 Mar;48(3):238-244. doi: 10.1038/ng.3489. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780609 Free PMC article.
Catch my drift? Making sense of genomic intra-tumour heterogeneity.
Sottoriva A, Barnes CP, Graham TA. Sottoriva A, et al. Among authors: graham ta. Biochim Biophys Acta Rev Cancer. 2017 Apr;1867(2):95-100. doi: 10.1016/j.bbcan.2016.12.003. Epub 2017 Jan 7. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28069394 Free PMC article. Review.
Resolving genetic heterogeneity in cancer.
Turajlic S, Sottoriva A, Graham T, Swanton C. Turajlic S, et al. Nat Rev Genet. 2019 Jul;20(7):404-416. doi: 10.1038/s41576-019-0114-6. Nat Rev Genet. 2019. PMID: 30918367 Review.
The co-evolution of the genome and epigenome in colorectal cancer.
Heide T, Househam J, Cresswell GD, Spiteri I, Lynn C, Mossner M, Kimberley C, Fernandez-Mateos J, Chen B, Zapata L, James C, Barozzi I, Chkhaidze K, Nichol D, Gunasri V, Berner A, Schmidt M, Lakatos E, Baker AM, Costa H, Mitchinson M, Piazza R, Jansen M, Caravagna G, Ramazzotti D, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Graham TA, Sottoriva A. Heide T, et al. Among authors: graham ta. Nature. 2022 Nov;611(7937):733-743. doi: 10.1038/s41586-022-05202-1. Epub 2022 Oct 26. Nature. 2022. PMID: 36289335 Free PMC article.
196 results