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966 results

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E2730, an uncompetitive γ-aminobutyric acid transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy.
Ali I, Silva J, Casillas-Espinosa PM, Braine E, Yamakawa GR, Hudson MR, Brady RD, Major B, Thergarajan P, Haskali MB, Wright DK, Jupp B, Vivash L, Shultz SR, Mychasiuk R, Kwan P, Jones NC, Fukushima K, Sachdev P, Cheng JY, O'Brien TJ. Ali I, et al. Epilepsia. 2023 Oct;64(10):2806-2817. doi: 10.1111/epi.17735. Epub 2023 Aug 11. Epilepsia. 2023. PMID: 37539645
Image data harmonization tools for the analysis of post-traumatic epilepsy development in preclinical multisite MRI studies.
Bhagavatula S, Cabeen R, Harris NG, Gröhn O, Wright DK, Garner R, Bennett A, Alba C, Martinez A, Ndode-Ekane XE, Andrade P, Paananen T, Ciszek R, Immonen R, Manninen E, Puhakka N, Tohka J, Heiskanen M, Ali I, Shultz SR, Casillas-Espinosa PM, Yamakawa GR, Jones NC, Hudson MR, Silva JC, Braine EL, Brady RD, Santana-Gomez CE, Smith GD, Staba R, O'Brien TJ, Pitkänen A, Duncan D; EpiBioS4Rx investigators. Bhagavatula S, et al. Epilepsy Res. 2023 Sep;195:107201. doi: 10.1016/j.eplepsyres.2023.107201. Epub 2023 Aug 2. Epilepsy Res. 2023. PMID: 37562146 Free PMC article.
Epilepsy phenotype and its reproducibility after lateral fluid percussion-induced traumatic brain injury in rats: Multicenter EpiBioS4Rx study project 1.
Ndode-Ekane XE, Ali I, Santana-Gomez C, Andrade P, Immonen R, Casillas-Espinosa P, Paananen T, Manninen E, Puhakka N, Smith G, Brady RD, Silva J, Braine E, Hudson M, Yamakawa GR, Jones NC, Shultz SR, Harris N, Wright DK, Gröhn O, Staba R, O'Brien TJ, Pitkänen A. Ndode-Ekane XE, et al. Epilepsia. 2024 Feb;65(2):511-526. doi: 10.1111/epi.17838. Epub 2023 Dec 12. Epilepsia. 2024. PMID: 38052475 Free article.
In vivo biomarkers of GABAergic function in epileptic rats treated with the GAT-1 inhibitor E2730.
Ali I, Jupp B, Hudson MR, Major B, Silva J, Yamakawa GR, Casillas-Espinosa PM, Braine E, Thergarajan P, Haskali MB, Vivash L, Brkljaca R, Shultz SR, Kwan P, Fukushima K, Sachdev P, Cheng JY, Mychasiuk R, Jones NC, Wright DK, OBrien TJ. Ali I, et al. Epilepsia. 2024 Nov;65(11):3376-3390. doi: 10.1111/epi.18119. Epub 2024 Sep 20. Epilepsia. 2024. PMID: 39302665
Pharmacokinetics and brain uptake of sodium selenate and selenium in naïve rats and a lateral fluid percussion injury rat model.
Li C, Casillas-Espinosa PM, Saletti PG, Chi T, Yamakawa G, Silva J, Hudson M, Liu W, Jones NC, Shultz SR, Ali I, Mishra U, Cloyd JC, Moshe SL, Galanopoulou AS, O'Brien TJ, Coles LD. Li C, et al. Pharmacol Res Perspect. 2024 Dec;12(6):e1256. doi: 10.1002/prp2.1256. Pharmacol Res Perspect. 2024. PMID: 39506350 Free PMC article.
Plasma microRNAs as prognostic biomarkers for development of severe epilepsy after experimental traumatic brain injury-EpiBioS4Rx Project 1 study.
Heiskanen M, Ndode-Ekane XE, Ali I, Santana-Gomez C, Puhakka N, Gupta SD, Andrade P, Immonen R, Casillas-Espinosa P, Manninen E, Smith G, Brady RD, Silva J, Braine E, Hudson M, Yamakawa GR, Jones NC, Shultz SR, Harris NG, Wright DK, Gröhn O, Staba RJ, O'Brien TJ, Pitkänen A. Heiskanen M, et al. Among authors: o brien tj. Epilepsia. 2024 Dec 11. doi: 10.1111/epi.18219. Online ahead of print. Epilepsia. 2024. PMID: 39661396
966 results