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Computational deconvolution of cell type-specific gene expression in COPD and IPF lungs reveals disease severity associations.
Ryu MH, Yun JH, Kim K, Gentili M, Ghosh A, Sciurba F, Barwick L, Limper A, Criner G, Brown KK, Wise R, Martinez FJ, Flaherty KR, Cho MH, Castaldi PJ, DeMeo DL, Silverman EK, Hersh CP, Morrow JD. Ryu MH, et al. Among authors: castaldi pj. BMC Genomics. 2024 Dec 18;25(1):1192. doi: 10.1186/s12864-024-11031-5. BMC Genomics. 2024. PMID: 39695952 Free PMC article.
Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Ghosh AJ, Hobbs BD, Yun JH, Saferali A, Moll M, Xu Z, Chase RP, Morrow J, Ziniti J, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner G, Brown KK, Wise R, Martinez FJ, McGoldrick D, Cho MH, DeMeo DL, Silverman EK, Castaldi PJ; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Hersh CP. Ghosh AJ, et al. Among authors: castaldi pj. Respir Res. 2022 Apr 21;23(1):97. doi: 10.1186/s12931-022-02013-w. Respir Res. 2022. PMID: 35449067 Free PMC article.
Partial correlation network analysis identifies coordinated gene expression within a regional cluster of COPD genome-wide association signals.
Gentili M, Glass K, Maiorino E, Hobbs BD, Xu Z, Castaldi PJ, Cho MH, Hersh CP, Qiao D, Morrow JD, Carey VJ, Platig J, Silverman EK. Gentili M, et al. Among authors: castaldi pj. PLoS Comput Biol. 2024 Oct 17;20(10):e1011079. doi: 10.1371/journal.pcbi.1011079. eCollection 2024 Oct. PLoS Comput Biol. 2024. PMID: 39418301 Free PMC article.
Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema.
Castaldi PJ, Dy J, Ross J, Chang Y, Washko GR, Curran-Everett D, Williams A, Lynch DA, Make BJ, Crapo JD, Bowler RP, Regan EA, Hokanson JE, Kinney GL, Han MK, Soler X, Ramsdell JW, Barr RG, Foreman M, van Beek E, Casaburi R, Criner GJ, Lutz SM, Rennard SI, Santorico S, Sciurba FC, DeMeo DL, Hersh CP, Silverman EK, Cho MH. Castaldi PJ, et al. Thorax. 2014 May;69(5):415-22. doi: 10.1136/thoraxjnl-2013-203601. Epub 2014 Feb 21. Thorax. 2014. PMID: 24563194 Free PMC article.
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH; NETT Genetics, ICGN, ECLIPSE and COPDGene Investigators. Cho MH, et al. Among authors: castaldi pj. Lancet Respir Med. 2014 Mar;2(3):214-25. doi: 10.1016/S2213-2600(14)70002-5. Epub 2014 Feb 7. Lancet Respir Med. 2014. PMID: 24621683 Free PMC article.
175 results