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Constitutive HIF-1α Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation.
Boix J, Knuever J, Niehoff N, Sen A, Pla-Martin D, Baris OR, Etich J, Brachvogel B, Kaul H, Isbrandt D, Soroka E, Bazzi H, Wenger RH, Giavalisco P, Wiesner RJ. Boix J, et al. Among authors: giavalisco p. J Invest Dermatol. 2024 Nov 22:S0022-202X(24)02951-8. doi: 10.1016/j.jid.2024.09.022. Online ahead of print. J Invest Dermatol. 2024. PMID: 39580109
Glutamine sensing licenses cholesterol synthesis.
Garcia BM, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, Kingma J, Gorbatenko A, Deshwal S, Veronese M, Scorrano L, Pearce E, Giavalisco P, Zelcer N, Pernas L. Garcia BM, et al. Among authors: giavalisco p. EMBO J. 2024 Dec;43(23):5837-5856. doi: 10.1038/s44318-024-00269-0. Epub 2024 Oct 21. EMBO J. 2024. PMID: 39433901 Free PMC article.
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver.
Aich A, Boshnakovska A, Witte S, Gall T, Unthan-Fechner K, Yousefi R, Chowdhury A, Dahal D, Methi A, Kaufmann S, Silbern I, Prochazka J, Nichtova Z, Palkova M, Raishbrook M, Koubkova G, Sedlacek R, Tröder SE, Zevnik B, Riedel D, Michanski S, Möbius W, Ströbel P, Lüchtenborg C, Giavalisco P, Urlaub H, Fischer A, Brügger B, Jakobs S, Rehling P. Aich A, et al. Among authors: giavalisco p. Nat Commun. 2024 Aug 12;15(1):6914. doi: 10.1038/s41467-024-51109-y. Nat Commun. 2024. PMID: 39134548 Free PMC article.
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity.
Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG. Jiang S, et al. Among authors: giavalisco p. Nat Metab. 2024 Jun;6(6):1024-1035. doi: 10.1038/s42255-024-01038-3. Epub 2024 Apr 30. Nat Metab. 2024. PMID: 38689023 Free PMC article.
Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.
Nikopoulou C, Kleinenkuhnen N, Parekh S, Sandoval T, Ziegenhain C, Schneider F, Giavalisco P, Donahue KF, Vesting AJ, Kirchner M, Bozukova M, Vossen C, Altmüller J, Wunderlich T, Sandberg R, Kondylis V, Tresch A, Tessarz P. Nikopoulou C, et al. Among authors: giavalisco p. Nat Aging. 2023 Nov;3(11):1430-1445. doi: 10.1038/s43587-023-00513-y. Epub 2023 Nov 9. Nat Aging. 2023. PMID: 37946043 Free PMC article.
Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression.
Grotehans N, McGarry L, Nolte H, Xavier V, Kroker M, Narbona-Pérez ÁJ, Deshwal S, Giavalisco P, Langer T, MacVicar T. Grotehans N, et al. Among authors: giavalisco p. EMBO J. 2023 Sep 18;42(18):e113256. doi: 10.15252/embj.2022113256. Epub 2023 Jul 13. EMBO J. 2023. PMID: 37439264 Free PMC article.
The regulation of sulfolipids under sulfur starvation.
Aarabi F, Salem MA, Arrivault S, Bulut M, Schöttler MA, Giavalisco P, Fernie AR, Hoefgen R. Aarabi F, et al. Among authors: giavalisco p. Plant Mol Biol. 2023 Jul;112(4-5):195-198. doi: 10.1007/s11103-023-01364-2. Epub 2023 Jun 22. Plant Mol Biol. 2023. PMID: 37347368 Free PMC article.
140 results