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Late-Stage Reshaping of Phage-Displayed Libraries to Macrocyclic and Bicyclic Landscapes using a Multipurpose Linchpin.
J Am Chem Soc. 2025 Jan 8;147(1):789-800. doi: 10.1021/jacs.4c13561. Epub 2024 Dec 19.
J Am Chem Soc. 2025.
PMID: 39702930
Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivo.
Wong JYK, Ekanayake AI, Kharchenko S, Kirberger SE, Qiu R, Kelich P, Sarkar S, Li J, Fernandez KX, Alvizo-Paez ER, Miao J, Kalhor-Monfared S, John JD, Kang H, Choi H, Nuss JM, Vederas JC, Lin YS, Macauley MS, Vukovic L, Pomerantz WCK, Derda R.
Wong JYK, et al. Among authors: ekanayake ai.
Nat Commun. 2023 Sep 13;14(1):5654. doi: 10.1038/s41467-023-41427-y.
Nat Commun. 2023.
PMID: 37704629
Free PMC article.
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Author Correction: Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivo.
Wong JYK, Ekanayake AI, Kharchenko S, Kirberger SE, Qiu R, Kelich P, Sarkar S, Li J, Fernandez KX, Alvizo-Paez ER, Miao J, Kalhor-Monfared S, John JD, Kang H, Choi H, Nuss JM, Vederas JC, Lin YS, Macauley MS, Vukovic L, Pomerantz WCK, Derda R.
Wong JYK, et al. Among authors: ekanayake ai.
Nat Commun. 2023 Nov 21;14(1):7587. doi: 10.1038/s41467-023-43517-3.
Nat Commun. 2023.
PMID: 37990013
Free PMC article.
No abstract available.
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Genetically Encoded Fragment-Based Discovery from Phage-Displayed Macrocyclic Libraries with Genetically Encoded Unnatural Pharmacophores.
Ekanayake AI, Sobze L, Kelich P, Youk J, Bennett NJ, Mukherjee R, Bhardwaj A, Wuest F, Vukovic L, Derda R.
Ekanayake AI, et al.
J Am Chem Soc. 2021 Apr 14;143(14):5497-5507. doi: 10.1021/jacs.1c01186. Epub 2021 Mar 30.
J Am Chem Soc. 2021.
PMID: 33784084
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