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Multiomics profiling of DNA methylation, microRNA, and mRNA in skeletal muscle from monozygotic twin pairs discordant for type 2 diabetes identifies dysregulated genes controlling metabolism.
Ling C, Vavakova M, Ahmad Mir B, Säll J, Perfilyev A, Martin M, Jansson PA, Davegårdh C, Asplund O, Hansson O, Vaag A, Nilsson E. Ling C, et al. Among authors: perfilyev a. BMC Med. 2024 Dec 2;22(1):572. doi: 10.1186/s12916-024-03789-y. BMC Med. 2024. PMID: 39623445 Free PMC article.
Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.
Rönn T, Ofori JK, Perfilyev A, Hamilton A, Pircs K, Eichelmann F, Garcia-Calzon S, Karagiannopoulos A, Stenlund H, Wendt A, Volkov P, Schulze MB, Mulder H, Eliasson L, Ruhrmann S, Bacos K, Ling C. Rönn T, et al. Among authors: perfilyev a. Nat Commun. 2023 Dec 12;14(1):8040. doi: 10.1038/s41467-023-43719-9. Nat Commun. 2023. PMID: 38086799 Free PMC article.
44 results