Robia SL - Search Results

1

Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of calcium.

Cleary SR, Teng ACT, Kongmeneck AD, Fang X, Phillips TA, Cho EE, Smith RA, Karkut P, Makarewich CA, Kekenes-Huskey PM, Gramolini AO, Robia SL. Cleary SR, et al. Among authors: robia sl. J Biol Chem. 2024 Dec 20:108118. doi: 10.1016/j.jbc.2024.108118. Online ahead of print. J Biol Chem. 2024. PMID: 39710323 Free article.

2

Another-regulin regulates cardiomyocyte calcium handling via integration of neuroendocrine signaling with SERCA2a activity.

Hassel KR, Gibson AM, Šeflová J, Cho EE, Blair NS, Van Raamsdonk CD, Anderson DM, Robia SL, Makarewich CA. Hassel KR, et al. Among authors: robia sl. J Mol Cell Cardiol. 2024 Dec;197:45-58. doi: 10.1016/j.yjmcc.2024.10.008. Epub 2024 Oct 20. J Mol Cell Cardiol. 2024. PMID: 39437886 Free PMC article.

3

Pathological mutations in the phospholamban cytoplasmic region affect its topology and dynamics modulating the extent of SERCA inhibition.

Weber DK, Reddy UV, Robia SL, Veglia G. Weber DK, et al. Among authors: robia sl. Biochim Biophys Acta Biomembr. 2024 Oct;1866(7):184370. doi: 10.1016/j.bbamem.2024.184370. Epub 2024 Jul 8. Biochim Biophys Acta Biomembr. 2024. PMID: 38986894

4

Phosphorylation of phospholamban promotes SERCA2a activation by dwarf open reading frame (DWORF).

Bovo E, Jamrozik T, Kahn D, Karkut P, Robia SL, Zima AV. Bovo E, et al. Among authors: robia sl. Cell Calcium. 2024 Jul;121:102910. doi: 10.1016/j.ceca.2024.102910. Epub 2024 May 24. Cell Calcium. 2024. PMID: 38823350

5

Protein carbonylation causes sarcoplasmic reticulum Ca²⁺ overload by increasing intracellular Na⁺ level in ventricular myocytes.

Bovo E, Seflova J, Robia SL, Zima AV. Bovo E, et al. Among authors: robia sl. Pflugers Arch. 2024 Jul;476(7):1077-1086. doi: 10.1007/s00424-024-02972-7. Epub 2024 May 20. Pflugers Arch. 2024. PMID: 38769127

6

Phospholamban inhibits the cardiac calcium pump by interrupting an allosteric activation pathway.

Cleary SR, Seflova J, Cho EE, Bisht K, Khandelia H, Espinoza-Fonseca LM, Robia SL. Cleary SR, et al. Among authors: robia sl. J Biol Chem. 2024 May;300(5):107267. doi: 10.1016/j.jbc.2024.107267. Epub 2024 Apr 6. J Biol Chem. 2024. PMID: 38583863 Free PMC article.

7

Protein carbonylation causes sarcoplasmic reticulum Ca2+ overload by increasing intracellular Na+ level in ventricular myocytes.

Bovo E, Seflova J, Robia SL, Zima AV. Bovo E, et al. Among authors: robia sl. Res Sq [Preprint]. 2024 Mar 1:rs.3.rs-3991887. doi: 10.21203/rs.3.rs-3991887/v1. Res Sq. 2024. Update in: Pflugers Arch. 2024 Jul;476(7):1077-1086. doi: 10.1007/s00424-024-02972-7 PMID: 38464201 Free PMC article. Updated. Preprint.

8

Mechanisms for cardiac calcium pump activation by its substrate and a synthetic allosteric modulator using fluorescence lifetime imaging.

Šeflová J, Cruz-Cortés C, Guerrero-Serna G, Robia SL, Espinoza-Fonseca LM. Šeflová J, et al. Among authors: robia sl. PNAS Nexus. 2023 Dec 22;3(1):pgad453. doi: 10.1093/pnasnexus/pgad453. eCollection 2024 Jan. PNAS Nexus. 2023. PMID: 38222469 Free PMC article.

9

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET.

Šeflová J, Schwarz JA, Smith AN, Svensson B, Blackwell DJ, Phillips TA, Nikolaienko R, Bovo E, Rebbeck RT, Zima AV, Thomas DD, Van Petegem F, Knollmann BC, Johnston JN, Robia SL, Cornea RL. Šeflová J, et al. Among authors: robia sl. ACS Chem Biol. 2023 Oct 20;18(10):2290-2299. doi: 10.1021/acschembio.3c00376. Epub 2023 Sep 28. ACS Chem Biol. 2023. PMID: 37769131 Free PMC article.

10

Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of cardiac calcium handling.

Cleary SR, Teng ACT, Kongmeneck AD, Fang X, Phillips TA, Cho EE, Kekenes-Huskey P, Gramolini AO, Robia SL. Cleary SR, et al. Among authors: robia sl. bioRxiv [Preprint]. 2023 May 28:2023.05.26.542463. doi: 10.1101/2023.05.26.542463. bioRxiv. 2023. Update in: J Biol Chem. 2024 Dec 20:108118. doi: 10.1016/j.jbc.2024.108118 PMID: 37292897 Free PMC article. Updated. Preprint.

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