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Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy.
Quek C, Pratapa A, Bai X, Al-Eryani G, Pires da Silva I, Mayer A, Bartonicek N, Harvey K, Maher NG, Conway JW, Kasalo RJ, Ben Cheikh B, Braubach O, Palendira U, Saw RPM, Stretch JR, Shannon KF, Menzies AM, Scolyer RA, Long GV, Swarbrick A, Wilmott JS. Quek C, et al. Among authors: braubach o. Cell Rep. 2024 Jul 23;43(7):114392. doi: 10.1016/j.celrep.2024.114392. Epub 2024 Jun 29. Cell Rep. 2024. PMID: 38944836 Free article.
A machine learning one-class logistic regression model to predict stemness for single cell transcriptomics and spatial omics.
Dezem FS, Marção M, Ben-Cheikh B, Nikulina N, Omotoso A, Burnett D, Coelho P, Hurley J, Gomez C, Phan-Everson T, Ong G, Martelotto L, Lewis ZR, George S, Braubach O, Malta TM, Plummer J. Dezem FS, et al. Among authors: braubach o. BMC Genomics. 2023 Nov 28;24(1):717. doi: 10.1186/s12864-023-09722-6. BMC Genomics. 2023. PMID: 38017371 Free PMC article.
Exposure to environmental airborne particulate matter caused wide-ranged transcriptional changes and accelerated Alzheimer's-related pathology: A mouse study.
Israel LL, Braubach O, Shatalova ES, Chepurna O, Sharma S, Klymyshyn D, Galstyan A, Chiechi A, Cox A, Herman D, Bliss B, Hasen I, Ting A, Arechavala R, Kleinman MT, Patil R, Holler E, Ljubimova JY, Koronyo-Hamaoui M, Sun T, Black KL. Israel LL, et al. Among authors: braubach o. Neurobiol Dis. 2023 Oct 15;187:106307. doi: 10.1016/j.nbd.2023.106307. Epub 2023 Sep 20. Neurobiol Dis. 2023. PMID: 37739136 Free article.
β-Amyloid targeting nanodrug for neuron-specific delivery of nucleic acids in Alzheimer's disease mouse models.
Israel LL, Sun T, Braubach O, Cox A, Shatalova ES, Rashid HM, Galstyan A, Grodzinski Z, Song XY, Chepurna O, Ljubimov VA, Chiechi A, Sharma S, Phebus C, Wang Y, Ljubimova JY, Black KL, Holler E. Israel LL, et al. Among authors: braubach o. J Control Release. 2023 Sep;361:636-658. doi: 10.1016/j.jconrel.2023.08.001. Epub 2023 Aug 17. J Control Release. 2023. PMID: 37544515 Free article.
A spatially resolved single-cell genomic atlas of the adult human breast.
Kumar T, Nee K, Wei R, He S, Nguyen QH, Bai S, Blake K, Pein M, Gong Y, Sei E, Hu M, Casasent AK, Thennavan A, Li J, Tran T, Chen K, Nilges B, Kashikar N, Braubach O, Ben Cheikh B, Nikulina N, Chen H, Teshome M, Menegaz B, Javaid H, Nagi C, Montalvan J, Lev T, Mallya S, Tifrea DF, Edwards R, Lin E, Parajuli R, Hanson S, Winocour S, Thompson A, Lim B, Lawson DA, Kessenbrock K, Navin N. Kumar T, et al. Among authors: braubach o. Nature. 2023 Aug;620(7972):181-191. doi: 10.1038/s41586-023-06252-9. Epub 2023 Jun 28. Nature. 2023. PMID: 37380767 Free PMC article.
A spatially resolved single cell genomic atlas of the adult human breast.
Kumar T, Nee K, Wei R, He S, Nguyen QH, Bai S, Blake K, Gong Y, Pein M, Sei E, Hu M, Casasent A, Thennavan A, Li J, Tran T, Chen K, Nilges B, Kashikar N, Braubach O, Cheikh BB, Nikulina N, Chen H, Teshome M, Menegaz B, Javaid H, Nagi C, Montalvan J, Tifrea DF, Edwards R, Lin E, Parajuli R, Winocour S, Thompson A, Lim B, Lawson DA, Kessenbrock K, Navin N. Kumar T, et al. Among authors: braubach o. bioRxiv [Preprint]. 2023 Apr 25:2023.04.22.537946. doi: 10.1101/2023.04.22.537946. bioRxiv. 2023. Update in: Nature. 2023 Aug;620(7972):181-191. doi: 10.1038/s41586-023-06252-9 PMID: 37163043 Free PMC article. Updated. Preprint.
Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy.
Sadeghirad H, Liu N, Monkman J, Ma N, Cheikh BB, Jhaveri N, Tan CW, Warkiani ME, Adams MN, Nguyen Q, Ladwa R, Braubach O, O'Byrne K, Davis M, Hughes BGM, Kulasinghe A. Sadeghirad H, et al. Among authors: braubach o. Front Immunol. 2023 Apr 3;14:1135489. doi: 10.3389/fimmu.2023.1135489. eCollection 2023. Front Immunol. 2023. PMID: 37153589 Free PMC article.
31 results