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CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
Teter OM, McQuade A, Hagan V, Liang W, Dräger NM, Sattler SM, Holmes BB, Castillo VC, Papakis V, Leng K, Boggess S, Nowakowski TJ, Wells J, Kampmann M. Teter OM, et al. Among authors: nowakowski tj. bioRxiv [Preprint]. 2024 Nov 17:2024.06.01.596962. doi: 10.1101/2024.06.01.596962. bioRxiv. 2024. PMID: 39605704 Free PMC article. Preprint.
An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes.
Furlanis E, Dai M, Leyva Garcia B, Vergara J, Pereira A, Pelkey K, Tran T, Gorissen BL, Vlachos A, Hairston A, Huang S, Dwivedi D, Du S, Wills S, McMahon J, Lee AT, Chang EF, Razzaq T, Qazi A, Vargish G, Yuan X, Caccavano A, Hunt S, Chittajallu R, McLean N, Hewit L, Paranzino E, Rice H, Cummins AC, Plotnikova A, Mohanty A, Tangen AC, Shin JH, Azadi R, Eldridge MAG, Alvarez VA, Averbeck BB, Alyahyay M, Reyes Vallejo T, Soheib M, Vattino LG, MacGregor CP, Banks E, Olah VJ, Naskar S, Hill S, Liebergall S, Badiani R, Hyde L, Xu Q, Allaway KC, Goldberg EM, Nowakowski TJ, Lee S, Takesian AE, Ibrahim LA, Iqbal A, McBain CJ, Dimidschstein J, Fishell G, Wang Y. Furlanis E, et al. Among authors: nowakowski tj. bioRxiv [Preprint]. 2024 Sep 6:2024.07.17.603924. doi: 10.1101/2024.07.17.603924. bioRxiv. 2024. PMID: 39091835 Free PMC article. Preprint.
Pathological microcircuits initiate epileptiform events in patient hippocampal slices.
Elliott MAT, Andrews JP, van der Molen T, Geng J, Spaeth A, Voituik K, Core C, Gillespie T, Sinervo A, Parks DF, Robbins A, Solís D, Chang EF, Nowakowski TJ, Teodorescu M, Haussler D, Sharf T. Elliott MAT, et al. Among authors: nowakowski tj. bioRxiv [Preprint]. 2024 Nov 14:2024.11.13.623525. doi: 10.1101/2024.11.13.623525. bioRxiv. 2024. PMID: 39605666 Free PMC article. Preprint.
Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1.
Yu D, Jain S, Wangzhou A, De Florencio S, Zhu B, Kim JY, Choi JJ, Paredes MF, Nowakowski TJ, Huang EJ, Piao X. Yu D, et al. Among authors: nowakowski tj. bioRxiv [Preprint]. 2024 Oct 20:2024.10.19.619180. doi: 10.1101/2024.10.19.619180. bioRxiv. 2024. PMID: 39464051 Free PMC article. Preprint.
Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces MR, Fan J, Heiman M, Harris K, Inoue F, Kellis M, Levine A, Lotfollahi M, Luo C, Maynard KR, Nitzan M, Ramani V, Satijia R, Schirmer L, Shen Y, Sun N, Green GS, Theis F, Wang X, Welch JD, Gokce O, Konopka G, Liddelow S, Macosko E, Ali Bayraktar O, Habib N, Nowakowski TJ. Bonev B, et al. Among authors: nowakowski tj. Nat Neurosci. 2025 Jan;28(1):216. doi: 10.1038/s41593-024-01858-2. Nat Neurosci. 2025. PMID: 39681663 No abstract available.
Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system.
Adameyko I, Bakken T, Bhaduri A, Chhatbar C, Filbin MG, Gate D, Hochgerner H, Kim CN, Krull J, La Manno G, Li Q, Linnarsson S, Ma Q, Mayer C, Menon V, Nano P, Prinz M, Quake S, Walsh CA, Yang J, Bayraktar OA, Gokce O, Habib N, Konopka G, Liddelow SA, Nowakowski TJ. Adameyko I, et al. Among authors: nowakowski tj. Nat Neurosci. 2024 Dec;27(12):2278-2291. doi: 10.1038/s41593-024-01827-9. Epub 2024 Dec 3. Nat Neurosci. 2024. PMID: 39627588 Review.
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces MR, Fan J, Heiman M, Harris K, Inoue F, Kellis M, Levine A, Lotfollahi M, Luo C, Maynard KR, Nitzan M, Ramani V, Satijia R, Schirmer L, Shen Y, Sun N, Green GS, Theis F, Wang X, Welch JD, Gokce O, Konopka G, Liddelow S, Macosko E, Ali Bayraktar O, Habib N, Nowakowski TJ. Bonev B, et al. Among authors: nowakowski tj. Nat Neurosci. 2024 Dec;27(12):2292-2309. doi: 10.1038/s41593-024-01806-0. Epub 2024 Dec 3. Nat Neurosci. 2024. PMID: 39627587 Review.
97 results