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The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Stolz DB, Wallace CT, Yu-Wei C, Franks J, Bose D, Shang P, Ambrosino HM, Dutton JR, Geng Z, Montford J, Ryu J, Rajasundaram D, Hose S, Sahel JA, Puertollano R, Finkel T, Zigler JS Jr, Sergeev Y, Watkins SC, Goetzman ES, Ferrington DA, Flores-Bellver M, Kaarniranta K, Sodhi A, Bharti K, Handa JT, Sinha D. Ghosh S, et al. Among authors: kedziora km. Nat Commun. 2024 Jul 21;15(1):6150. doi: 10.1038/s41467-024-50500-z. Nat Commun. 2024. PMID: 39034314 Free PMC article.
ATR promotes mTORC1 activity via de novo cholesterol synthesis.
Tangudu NK, Grumet AN, Fang R, Buj R, Cole AR, Uboveja A, Amalric A, Yang B, Huang Z, Happe C, Sun M, Gelhaus SL, MacDonald ML, Hempel N, Snyder NW, Kedziora KM, Valvezan AJ, Aird KM. Tangudu NK, et al. Among authors: kedziora km. bioRxiv [Preprint]. 2024 Oct 24:2023.10.27.564195. doi: 10.1101/2023.10.27.564195. bioRxiv. 2024. PMID: 37961201 Free PMC article. Preprint.
An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal stem cells.
Cotton MJ, Ariel P, Chen K, Walcott VA, Dixit M, Breau KA, Hinesley CM, Kedziora K, Tang CY, Zheng A, Magness ST, Burclaff J. Cotton MJ, et al. Among authors: kedziora k. bioRxiv [Preprint]. 2023 Oct 10:2023.10.09.561410. doi: 10.1101/2023.10.09.561410. bioRxiv. 2023. Update in: Sci Rep. 2024 Jul 2;14(1):15195. doi: 10.1038/s41598-024-66042-9 PMID: 37873351 Free PMC article. Updated. Preprint.
70 results