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BRD4 inhibition rewires cardiac macrophages toward a protective phenotype marked by low MHC class II expression.
Schuetze KB, Stratton MS, Bagchi RA, Hobby ARH, Felisbino MB, Rubino M, Toni LS, Reges C, Cavasin MA, McMahan RH, Alexanian M, Vagnozzi RJ, McKinsey TA. Schuetze KB, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2024 Dec 23. doi: 10.1152/ajpheart.00438.2024. Online ahead of print. Am J Physiol Heart Circ Physiol. 2024. PMID: 39716819
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Demos-Davies KM, Ferguson BS, Cavasin MA, Mahaffey JH, Williams SM, Spiltoir JI, Schuetze KB, Horn TR, Chen B, Ferrara C, Scellini B, Piroddi N, Tesi C, Poggesi C, Jeong MY, McKinsey TA. Demos-Davies KM, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H252-8. doi: 10.1152/ajpheart.00149.2014. Epub 2014 May 23. Am J Physiol Heart Circ Physiol. 2014. PMID: 24858848 Free PMC article.
Epigenetic regulation of cardiac fibrosis.
Stratton MS, McKinsey TA. Stratton MS, et al. Among authors: mckinsey ta. J Mol Cell Cardiol. 2016 Mar;92:206-13. doi: 10.1016/j.yjmcc.2016.02.011. Epub 2016 Feb 12. J Mol Cell Cardiol. 2016. PMID: 26876451 Free PMC article. Review.
BRD4 inhibition for the treatment of pathological organ fibrosis.
Stratton MS, Haldar SM, McKinsey TA. Stratton MS, et al. Among authors: mckinsey ta. F1000Res. 2017 Jun 28;6:F1000 Faculty Rev-1015. doi: 10.12688/f1000research.11339.1. eCollection 2017. F1000Res. 2017. PMID: 28721198 Free PMC article. Review.
Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.
Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA. Stratton MS, et al. Among authors: mckinsey ta. Circ Res. 2019 Sep 13;125(7):662-677. doi: 10.1161/CIRCRESAHA.119.315125. Epub 2019 Aug 14. Circ Res. 2019. PMID: 31409188 Free PMC article.
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
Ferguson BS, Wennersten SA, Demos-Davies KM, Rubino M, Robinson EL, Cavasin MA, Stratton MS, Kidger AM, Hu T, Keyse SM, McKnight RA, Lane RH, Nozik ES, Weiser-Evans MCM, McKinsey TA. Ferguson BS, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2021 Aug 1;321(2):H382-H389. doi: 10.1152/ajpheart.00115.2021. Epub 2021 Jun 18. Am J Physiol Heart Circ Physiol. 2021. PMID: 34142888 Free PMC article.
Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype.
Hobby ARH, Berretta RM, Eaton DM, Kubo H, Feldsott E, Yang Y, Headrick AL, Koch KA, Rubino M, Kurian J, Khan M, Tan Y, Mohsin S, Gallucci S, McKinsey TA, Houser SR. Hobby ARH, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2021 Oct 1;321(4):H684-H701. doi: 10.1152/ajpheart.00304.2021. Epub 2021 Aug 20. Am J Physiol Heart Circ Physiol. 2021. PMID: 34415185 Free PMC article.
186 results