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Page 1
BRAFV600E/pTERT double mutated papillary thyroid cancers exhibit immune gene suppression.
Sigarteu Chindris AM, Rivera M, Ma Y, Nair A, Liu Y, Wang X, Necela BM, Kachergus JM, Casler JD, Brett C, Rivas Mejia AM, Bernet VJ, Copland JA 3rd, Knutson KL, Thompson EA, Smallridge RC. Sigarteu Chindris AM, et al. Among authors: kachergus jm. Front Endocrinol (Lausanne). 2024 Dec 9;15:1440722. doi: 10.3389/fendo.2024.1440722. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39717106 Free PMC article.
Discrete class I molecules on brain endothelium differentially regulate neuropathology in experimental cerebral malaria.
Fain CE, Zheng J, Jin F, Ayasoufi K, Wu Y, Lilley MT, Dropik AR, Wolf DM, Rodriguez RC, Aibaidula A, Tritz ZP, Bouchal SM, Pewe LL, Urban SL, Chen Y, Chang SY, Hansen MJ, Kachergus JM, Shi J, Thompson EA, Jensen HE, Harty JT, Parney IF, Sun J, Wu LJ, Johnson AJ. Fain CE, et al. Among authors: kachergus jm. Brain. 2024 Feb 1;147(2):566-589. doi: 10.1093/brain/awad319. Brain. 2024. PMID: 37776513
Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer.
Carter JM, Chumsri S, Hinerfeld DA, Ma Y, Wang X, Zahrieh D, Hillman DW, Tenner KS, Kachergus JM, Brauer HA, Warren SE, Henderson D, Shi J, Liu Y, Joensuu H, Lindman H, Leon-Ferre RA, Boughey JC, Liu MC, Ingle JN, Kalari KR, Couch FJ, Knutson KL, Goetz MP, Perez EA, Thompson EA. Carter JM, et al. Among authors: kachergus jm. Nat Commun. 2023 Apr 18;14(1):2215. doi: 10.1038/s41467-023-37806-0. Nat Commun. 2023. PMID: 37072398 Free PMC article.
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance.
Zhang X, Pearsall VM, Carver CM, Atkinson EJ, Clarkson BDS, Grund EM, Baez-Faria M, Pavelko KD, Kachergus JM, White TA, Johnson RK, Malo CS, Gonzalez-Suarez AM, Ayasoufi K, Johnson KO, Tritz ZP, Fain CE, Khadka RH, Ogrodnik M, Jurk D, Zhu Y, Tchkonia T, Revzin A, Kirkland JL, Johnson AJ, Howe CL, Thompson EA, LeBrasseur NK, Schafer MJ. Zhang X, et al. Among authors: kachergus jm. Nat Commun. 2022 Sep 27;13(1):5671. doi: 10.1038/s41467-022-33226-8. Nat Commun. 2022. PMID: 36167854 Free PMC article.
Evidence of cerebellar TDP-43 loss of function in FTLD-TDP.
Pickles S, Gendron TF, Koike Y, Yue M, Song Y, Kachergus JM, Shi J, DeTure M, Thompson EA, Oskarsson B, Graff-Radford NR, Boeve BF, Petersen RC, Wszolek ZK, Josephs KA, Dickson DW, Petrucelli L, Cook CN, Prudencio M. Pickles S, et al. Among authors: kachergus jm. Acta Neuropathol Commun. 2022 Jul 25;10(1):107. doi: 10.1186/s40478-022-01408-6. Acta Neuropathol Commun. 2022. PMID: 35879741 Free PMC article.
Characteristics and Spatially Defined Immune (micro)landscapes of Early-stage PD-L1-positive Triple-negative Breast Cancer.
Carter JM, Polley MC, Leon-Ferre RA, Sinnwell J, Thompson KJ, Wang X, Ma Y, Zahrieh D, Kachergus JM, Solanki M, Boughey JC, Liu MC, Ingle JN, Kalari KR, Couch FJ, Thompson EA, Goetz MP. Carter JM, et al. Among authors: kachergus jm. Clin Cancer Res. 2021 Oct 15;27(20):5628-5637. doi: 10.1158/1078-0432.CCR-21-0343. Epub 2021 Jun 9. Clin Cancer Res. 2021. PMID: 34108182 Free PMC article.
Association of Genetic Variants at TRPC6 With Chemotherapy-Related Heart Failure.
Norton N, Crook JE, Wang L, Olson JE, Kachergus JM, Serie DJ, Necela BM, Borgman PG, Advani PP, Ray JC, Landolfo C, Di Florio DN, Hill AR, Bruno KA, Fairweather D. Norton N, et al. Among authors: kachergus jm. Front Cardiovasc Med. 2020 Aug 13;7:142. doi: 10.3389/fcvm.2020.00142. eCollection 2020. Front Cardiovasc Med. 2020. PMID: 32903434 Free PMC article.
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus JM, Shi J, Heckman MG, Spiegel MR, Cook C, Song Y, Yue M, Daughrity LM, Carlomagno Y, Jansen-West K, de Castro CF, DeTure M, Koga S, Wang YC, Sivakumar P, Bodo C, Candalija A, Talbot K, Selvaraj BT, Burr K, Chandran S, Newcombe J, Lashley T, Hubbard I, Catalano D, Kim D, Propp N, Fennessey S; NYGC ALS Consortium; Fagegaltier D, Phatnani H, Secrier M, Fisher EM, Oskarsson B, van Blitterswijk M, Rademakers R, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Josephs KA, Thompson EA, Raj T, Ward M, Dickson DW, Gendron TF, Fratta P, Petrucelli L. Prudencio M, et al. Among authors: kachergus jm. J Clin Invest. 2020 Nov 2;130(11):6080-6092. doi: 10.1172/JCI139741. J Clin Invest. 2020. PMID: 32790644 Free PMC article.
Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers.
Jackson JL, Finch NA, Baker MC, Kachergus JM, DeJesus-Hernandez M, Pereira K, Christopher E, Prudencio M, Heckman MG, Thompson EA, Dickson DW, Shah J, Oskarsson B, Petrucelli L, Rademakers R, van Blitterswijk M. Jackson JL, et al. Among authors: kachergus jm. Mol Neurodegener. 2020 Jan 30;15(1):7. doi: 10.1186/s13024-020-0359-8. Mol Neurodegener. 2020. PMID: 32000838 Free PMC article.
44 results