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A multi-model approach identifies ALW-II-41-27 as a promising therapy for osteoarthritis-associated inflammation and endochondral ossification.
Ferrao Blanco MN, Lesage R, Kops N, Fahy N, Bekedam FT, Chavli A, Bastiaansen-Jenniskens YM, Geris L, Chambers MG, Pitsillides AA, Narcisi R, van Osch GJVM. Ferrao Blanco MN, et al. Among authors: chavli a. Heliyon. 2024 Dec 4;10(23):e40871. doi: 10.1016/j.heliyon.2024.e40871. eCollection 2024 Dec 15. Heliyon. 2024. PMID: 39717596 Free PMC article.
Intra-articular injection of triamcinolone acetonide sustains macrophage levels and aggravates osteophytosis during degenerative joint disease in mice.
Ferrao Blanco MN, Bastiaansen Jenniskens YM, Kops N, Chavli A, Narcisi R, Botter SM, Leenen PJM, van Osch GJVM, Fahy N. Ferrao Blanco MN, et al. Among authors: chavli a. Br J Pharmacol. 2022 Jun;179(11):2771-2784. doi: 10.1111/bph.15780. Epub 2022 Jan 26. Br J Pharmacol. 2022. PMID: 34907535 Free PMC article.