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Bcl‑xL‑specific BH3 mimetic A‑1331852 suppresses proliferation of fluorouracil‑resistant colorectal cancer cells by inducing apoptosis.
Kato A, Takahashi H, Asai H, Uehara S, Harata S, Fujii Y, Watanabe K, Yanagita T, Suzuki T, Ushigome H, Shiga K, Yamakawa Y, Ogawa R, Mitsui A, Matsuo Y, Takiguchi S. Kato A, et al. Among authors: takahashi h. Oncol Rep. 2025 Feb;53(2):26. doi: 10.3892/or.2024.8859. Epub 2024 Dec 24. Oncol Rep. 2025. PMID: 39717947 Free PMC article.
Escin inhibits angiogenesis by suppressing interleukin‑8 and vascular endothelial growth factor production by blocking nuclear factor‑κB activation in pancreatic cancer cell lines.
Omi K, Matsuo Y, Ueda G, Aoyama Y, Kato T, Hayashi Y, Imafuji H, Saito K, Tsuboi K, Morimoto M, Ogawa R, Takahashi H, Takiguchi S. Omi K, et al. Among authors: takahashi h. Oncol Rep. 2021 May;45(5):55. doi: 10.3892/or.2021.8006. Epub 2021 Mar 24. Oncol Rep. 2021. PMID: 33760162 Free PMC article.
Chitinase 3-like 1 secreted from cancer-associated fibroblasts promotes tumor angiogenesis via interleukin-8 secretion in colorectal cancer.
Watanabe K, Shiga K, Maeda A, Harata S, Yanagita T, Suzuki T, Ushigome H, Maeda Y, Hirokawa T, Ogawa R, Hara M, Takahashi H, Matsuo Y, Mitsui A, Kimura M, Takiguchi S. Watanabe K, et al. Among authors: takahashi h. Int J Oncol. 2022 Jan;60(1):3. doi: 10.3892/ijo.2021.5293. Epub 2021 Dec 16. Int J Oncol. 2022. PMID: 34913066 Free PMC article.
ATR inhibitor AZD6738 increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting repair of DNA damage.
Suzuki T, Hirokawa T, Maeda A, Harata S, Watanabe K, Yanagita T, Ushigome H, Nakai N, Maeda Y, Shiga K, Ogawa R, Mitsui A, Kimura M, Matsuo Y, Takahashi H, Takiguchi S. Suzuki T, et al. Among authors: takahashi h. Oncol Rep. 2022 Apr;47(4):78. doi: 10.3892/or.2022.8289. Epub 2022 Feb 22. Oncol Rep. 2022. PMID: 35191521 Free PMC article.
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