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129,897 results

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LDB1 establishes multi-enhancer networks to regulate gene expression.
Aboreden NG, Lam JC, Goel VY, Wang S, Wang X, Midla SC, Quijano A, Keller CA, Giardine BM, Hardison RC, Zhang H, Hansen AS, Blobel GA. Aboreden NG, et al. Among authors: zhang h. Mol Cell. 2024 Dec 18:S1097-2765(24)00992-4. doi: 10.1016/j.molcel.2024.11.037. Online ahead of print. Mol Cell. 2024. PMID: 39721581
Chromatin structure dynamics during the mitosis-to-G1 phase transition.
Zhang H, Emerson DJ, Gilgenast TG, Titus KR, Lan Y, Huang P, Zhang D, Wang H, Keller CA, Giardine B, Hardison RC, Phillips-Cremins JE, Blobel GA. Zhang H, et al. Among authors: zhang d. Nature. 2019 Dec;576(7785):158-162. doi: 10.1038/s41586-019-1778-y. Epub 2019 Nov 27. Nature. 2019. PMID: 31776509 Free PMC article.
Alteration of genome folding via contact domain boundary insertion.
Zhang D, Huang P, Sharma M, Keller CA, Giardine B, Zhang H, Gilgenast TG, Phillips-Cremins JE, Hardison RC, Blobel GA. Zhang D, et al. Among authors: zhang h. Nat Genet. 2020 Oct;52(10):1076-1087. doi: 10.1038/s41588-020-0680-8. Epub 2020 Aug 31. Nat Genet. 2020. PMID: 32868908 Free PMC article.
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system.
Luan J, Xiang G, Gómez-García PA, Tome JM, Zhang Z, Vermunt MW, Zhang H, Huang A, Keller CA, Giardine BM, Zhang Y, Lan Y, Lis JT, Lakadamyali M, Hardison RC, Blobel GA. Luan J, et al. Among authors: zhang z, zhang h, zhang y. Cell Rep. 2021 Feb 23;34(8):108783. doi: 10.1016/j.celrep.2021.108783. Cell Rep. 2021. PMID: 33626344 Free PMC article.
CTCF blocks antisense transcription initiation at divergent promoters.
Luan J, Vermunt MW, Syrett CM, Coté A, Tome JM, Zhang H, Huang A, Luppino JM, Keller CA, Giardine BM, Zhang S, Dunagin MC, Zhang Z, Joyce EF, Lis JT, Raj A, Hardison RC, Blobel GA. Luan J, et al. Among authors: zhang s, zhang z, zhang h. Nat Struct Mol Biol. 2022 Nov;29(11):1136-1144. doi: 10.1038/s41594-022-00855-y. Epub 2022 Nov 11. Nat Struct Mol Biol. 2022. PMID: 36369346 Free PMC article.
Genome folding principles revealed in condensin-depleted mitotic chromosomes.
Zhao H, Lin Y, Lin E, Liu F, Shu L, Jing D, Wang B, Wang M, Shan F, Zhang L, Lam JC, Midla SC, Giardine BM, Keller CA, Hardison RC, Blobel GA, Zhang H. Zhao H, et al. Among authors: zhang l, zhang h. bioRxiv [Preprint]. 2023 Nov 13:2023.11.09.566494. doi: 10.1101/2023.11.09.566494. bioRxiv. 2023. Update in: Nat Genet. 2024 Jun;56(6):1213-1224. doi: 10.1038/s41588-024-01759-x PMID: 38014261 Free PMC article. Updated. Preprint.
Genome folding principles uncovered in condensin-depleted mitotic chromosomes.
Zhao H, Lin Y, Lin E, Liu F, Shu L, Jing D, Wang B, Wang M, Shan F, Zhang L, Lam JC, Midla SC, Giardine BM, Keller CA, Hardison RC, Blobel GA, Zhang H. Zhao H, et al. Among authors: zhang l, zhang h. Nat Genet. 2024 Jun;56(6):1213-1224. doi: 10.1038/s41588-024-01759-x. Epub 2024 May 27. Nat Genet. 2024. PMID: 38802567
BRD4 orchestrates genome folding to promote neural crest differentiation.
Linares-Saldana R, Kim W, Bolar NA, Zhang H, Koch-Bojalad BA, Yoon S, Shah PP, Karnay A, Park DS, Luppino JM, Nguyen SC, Padmanabhan A, Smith CL, Poleshko A, Wang Q, Li L, Srivastava D, Vahedi G, Eom GH, Blobel GA, Joyce EF, Jain R. Linares-Saldana R, et al. Among authors: zhang h. Nat Genet. 2021 Oct;53(10):1480-1492. doi: 10.1038/s41588-021-00934-8. Epub 2021 Oct 5. Nat Genet. 2021. PMID: 34611363 Free PMC article.
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