McCarthy FO - Search Results

1

Isoquinolinequinone N-oxides with diverging mechanisms of action induce collateral sensitivity against multidrug resistant cancer cells.

Barbosa MAG, Kruschel RD, Almeida MJ, Pereira RF, Xavier CPR, McCarthy FO, Vasconcelos MH. Barbosa MAG, et al. Among authors: mccarthy fo. Eur J Pharmacol. 2024 Dec 24:177234. doi: 10.1016/j.ejphar.2024.177234. Online ahead of print. Eur J Pharmacol. 2024. PMID: 39725135

2

Discovery of Potent Isoquinolinequinone N-Oxides to Overcome Cancer Multidrug Resistance.

Kruschel RD, Barbosa MAG, Almeida MJ, Xavier CPR, Vasconcelos MH, McCarthy FO. Kruschel RD, et al. Among authors: mccarthy fo. J Med Chem. 2024 Aug 22;67(16):13909-13924. doi: 10.1021/acs.jmedchem.4c00705. Epub 2024 Aug 2. J Med Chem. 2024. PMID: 39093920 Free PMC article.

3

Isoquinolinequinone N-oxides as anticancer agents effective against drug resistant cell lines.

Kruschel RD, Buzid A, Khandavilli UBR, Lawrence SE, Glennon JD, McCarthy FO. Kruschel RD, et al. Among authors: mccarthy fo. Org Biomol Chem. 2020 Jan 22;18(3):557-568. doi: 10.1039/c9ob02441g. Org Biomol Chem. 2020. PMID: 31894828

4

Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents.

Pierce LT, Cahill MM, Winfield HJ, McCarthy FO. Pierce LT, et al. Among authors: mccarthy fo. Eur J Med Chem. 2012 Oct;56:292-300. doi: 10.1016/j.ejmech.2012.08.002. Epub 2012 Aug 10. Eur J Med Chem. 2012. PMID: 22910137

5

Synthesis and Evaluation of Novel Ellipticines and Derivatives as Inhibitors of Phytophthora infestans.

McKee ML, Zheng L, O'Sullivan EC, Kehoe RA, Doyle Prestwich BM, Mackrill JJ, McCarthy FO. McKee ML, et al. Among authors: mccarthy fo. Pathogens. 2020 Jul 10;9(7):558. doi: 10.3390/pathogens9070558. Pathogens. 2020. PMID: 32664299 Free PMC article.

6

Novel 11-Substituted Ellipticines as Potent Anticancer Agents with Divergent Activity against Cancer Cells.

Miller CM, O'Sullivan EC, McCarthy FO. Miller CM, et al. Among authors: mccarthy fo. Pharmaceuticals (Basel). 2019 Jun 14;12(2):90. doi: 10.3390/ph12020090. Pharmaceuticals (Basel). 2019. PMID: 31207878 Free PMC article.

7

Ellipticine derivative induces potent cytostatic effect in acute myeloid leukaemia cells.

Russell EG, O'Sullivan EC, Miller CM, Stanicka J, McCarthy FO, Cotter TG. Russell EG, et al. Among authors: mccarthy fo. Invest New Drugs. 2014 Dec;32(6):1113-22. doi: 10.1007/s10637-014-0140-3. Epub 2014 Aug 10. Invest New Drugs. 2014. PMID: 25107543

8

Synthesis and biological evaluation of novel isoellipticine derivatives and salts.

Miller CM, O'Sullivan EC, Devine KJ, McCarthy FO. Miller CM, et al. Among authors: mccarthy fo. Org Biomol Chem. 2012 Oct 21;10(39):7912-21. doi: 10.1039/c2ob26181b. Org Biomol Chem. 2012. PMID: 22940706

9

7-formyl-10-methylisoellipticine, a novel ellipticine derivative, induces mitochondrial reactive oxygen species (ROS) and shows anti-leukaemic activity in mice.

Russell EG, Guo J, O'Sullivan EC, O'Driscoll CM, McCarthy FO, Cotter TG. Russell EG, et al. Among authors: mccarthy fo. Invest New Drugs. 2016 Feb;34(1):15-23. doi: 10.1007/s10637-015-0302-y. Epub 2015 Nov 12. Invest New Drugs. 2016. PMID: 26559431

10

Recent advances in Phytosterol Oxidation Products.

O'Callaghan Y, McCarthy FO, O'Brien NM. O'Callaghan Y, et al. Among authors: mccarthy fo. Biochem Biophys Res Commun. 2014 Apr 11;446(3):786-91. doi: 10.1016/j.bbrc.2014.01.148. Epub 2014 Jan 31. Biochem Biophys Res Commun. 2014. PMID: 24491535 Review.

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