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A stratified treatment algorithm in psychiatry: a program on stratified pharmacogenomics in severe mental illness (Psych-STRATA): concept, objectives and methodologies of a multidisciplinary project funded by Horizon Europe.
Baune BT, Fromme SE, Aberg M, Adli M, Afantitis A, Akkouh I, Andreassen OA, Angulo C, Barlati S, Brasso C, Bucci P, Budde M, Buspavanich P, Cavone V, Demyttenaere K, Diaz-Caneja CM, Dierssen M, Djurovic S, Driessen M, Ebner-Priemer UW, Engelmann J, Englisch S, Fabbri C, Fossati P, Fröhlich H, Gasser S, Gottlieb N, Heirman E, Hofer A, Howes O, Ilzarbe L, Jeung-Maarse H, Kessing LV, Kockler TD, Landén M, Levi L, Lieb K, Lorenzon N, Luykx J, Manchia M, Martinez de Lagran M, Minelli A, Moreno C, Mucci A, Müller-Myhsok B, Nilsson P, Okhuijsen-Pfeifer C, Papavasileiou KD, Papiol S, Pardinas AF, Paribello P, Pisanu C, Potier MC, Reif A, Ricken R, Ripke S, Rocca P, Scherrer D, Schiweck C, Schubert KO, Schulze TG, Serretti A, Squassina A, Stephan C, Tsoumanis A, Van der Eycken E, Vieta E, Vita A, Walters JTR, Weichert D, Weiser M, Willcocks IR, Winter-van Rossum I, Young AH, Ziller MJ. Baune BT, et al. Among authors: pardinas af. Eur Arch Psychiatry Clin Neurosci. 2024 Dec 27. doi: 10.1007/s00406-024-01944-3. Online ahead of print. Eur Arch Psychiatry Clin Neurosci. 2024. PMID: 39729102
Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores.
Kappel DB, Legge SE, Hubbard L, Willcocks IR, O'Connell KS, Smith RL, Molden E, Andreassen OA, King A, Jansen J, Helthuis M, Owen MJ, O'Donovan MC, Walters JTR, Pardiñas AF. Kappel DB, et al. Among authors: pardinas af. Biol Psychiatry. 2023 Jan 15;93(2):149-156. doi: 10.1016/j.biopsych.2022.07.014. Epub 2022 Aug 5. Biol Psychiatry. 2023. PMID: 36244804 Free PMC article.
How Real-World Data Can Facilitate the Development of Precision Medicine Treatment in Psychiatry.
Koch E, Pardiñas AF, O'Connell KS, Selvaggi P, Camacho Collados J, Babic A, Marshall SE, Van der Eycken E, Angulo C, Lu Y, Sullivan PF, Dale AM, Molden E, Posthuma D, White N, Schubert A, Djurovic S, Heimer H, Stefánsson H, Stefánsson K, Werge T, Sønderby I, O'Donovan MC, Walters JTR, Milani L, Andreassen OA. Koch E, et al. Among authors: pardinas af. Biol Psychiatry. 2024 Oct 1;96(7):543-551. doi: 10.1016/j.biopsych.2024.01.001. Epub 2024 Jan 5. Biol Psychiatry. 2024. PMID: 38185234 Free article. Review.
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.
Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M, Brandt H, Chang X, Chen WJ, Chen HC, Crawford S, Crow S, DiBlasi E, Duriez P, Fernández-Aranda F, Fichter MM, Gallinger S, Glatt SJ, Gorwood P, Guo Y, Hakonarson H, Halmi KA, Hwu HG, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Klump KL, Li D, Liao SC, Lieb K, Lilenfeld L, Liu CM, Magistretti PJ, Marshall CR, Mitchell JE, Monson ET, Myers RM, Pinto D, Powers A, Ramoz N, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Strober M, Thornton LM, Treasure J, Tsuang MT, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Air TM, Alda M, Alfredsson L, Andreassen OA, Anjorin A, Appadurai V, Soler Artigas M, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Bosch R, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Casas M, Castelao E, Cervilla JA, Chaumette B, Cichon S, Corvin A, … See abstract for full author list ➔ Mullins N, et al. Biol Psychiatry. 2022 Feb 1;91(3):313-327. doi: 10.1016/j.biopsych.2021.05.029. Epub 2021 Sep 9. Biol Psychiatry. 2022. PMID: 34861974 Free PMC article.
Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis.
Pistis G, Vázquez-Bourgon J, Fournier M, Jenni R, Cleusix M, Papiol S, Smart SE, Pardiñas AF, Walters JTR, MacCabe JH, Kutalik Z, Conus P, Crespo-Facorro B, Q Do K. Pistis G, et al. Among authors: pardinas af. Mol Psychiatry. 2022 Dec;27(12):5135-5143. doi: 10.1038/s41380-022-01779-1. Epub 2022 Sep 21. Mol Psychiatry. 2022. PMID: 36131045 Free PMC article.
Genetic association of FMRP targets with psychiatric disorders.
Clifton NE, Rees E, Holmans PA, Pardiñas AF, Harwood JC, Di Florio A, Kirov G, Walters JTR, O'Donovan MC, Owen MJ, Hall J, Pocklington AJ. Clifton NE, et al. Among authors: pardinas af. Mol Psychiatry. 2021 Jul;26(7):2977-2990. doi: 10.1038/s41380-020-00912-2. Epub 2020 Oct 19. Mol Psychiatry. 2021. PMID: 33077856 Free PMC article.
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC); Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J. Pardiñas AF, et al. JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001/jamapsychiatry.2021.3799. JAMA Psychiatry. 2022. PMID: 35019943 Free PMC article.
94 results