Kirschning A - Search Results

1

Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives.

Struwe H, Nguyen T, Schwörer S, Droste J, Spinck H, Kirschning A. Struwe H, et al. Among authors: kirschning a. Biochemistry. 2024 Dec 28. doi: 10.1021/acs.biochem.4c00589. Online ahead of print. Biochemistry. 2024. PMID: 39731539

2

Sesquiterpene Backbones Generated by Sesquiterpene Cyclases: Formation of iso-Caryolan-1-ol and an Isoclovane.

Struwe H, Schrödter F, Spinck H, Kirschning A. Struwe H, et al. Among authors: kirschning a. Org Lett. 2023 Dec 8;25(48):8575-8579. doi: 10.1021/acs.orglett.3c03383. Epub 2023 Nov 27. Org Lett. 2023. PMID: 38011332 Free PMC article.

3

Telescoping a Prenyltransferase and a Diterpene Synthase to Transform Unnatural FPP Derivatives to Diterpenoids.

Struwe H, Li H, Schrödter F, Höft L, Fohrer J, Dickschat JS, Kirschning A. Struwe H, et al. Among authors: kirschning a. Org Lett. 2024 Jul 19;26(28):5888-5892. doi: 10.1021/acs.orglett.4c01670. Epub 2024 Jul 8. Org Lett. 2024. PMID: 38976793 Free PMC article.

4

Sesquiterpene Cyclase BcBOT2 Promotes the Unprecedented Wagner-Meerwein Rearrangement of the Methoxy Group.

Moeller M, Dhar D, Dräger G, Özbasi M, Struwe H, Wildhagen M, Davari MD, Beutel S, Kirschning A. Moeller M, et al. Among authors: kirschning a. J Am Chem Soc. 2024 Jul 3;146(26):17838-17846. doi: 10.1021/jacs.4c03386. Epub 2024 Jun 18. J Am Chem Soc. 2024. PMID: 38888422 Free PMC article.

5

Cyclopropylmethyldiphosphates are substrates for sesquiterpene synthases: experimental and theoretical results.

Tran CD, Dräger G, Struwe HF, Siedenberg L, Vasisth S, Grunenberg J, Kirschning A. Tran CD, et al. Among authors: kirschning a. Org Biomol Chem. 2022 Oct 12;20(39):7833-7839. doi: 10.1039/d2ob01279k. Org Biomol Chem. 2022. PMID: 36169604

6

The Noncompetitive Effect of Gambogic Acid Displaces Fluorescence-Labeled ATP but Requires ATP for Binding to Hsp90/HtpG.

Yue Q, Stahl F, Plettenburg O, Kirschning A, Warnecke A, Zeilinger C. Yue Q, et al. Among authors: kirschning a. Biochemistry. 2018 May 8;57(18):2601-2605. doi: 10.1021/acs.biochem.8b00155. Epub 2018 Apr 24. Biochemistry. 2018. PMID: 29664615

7

Harms V, Ravkina V, Kirschning A. Harms V, et al. Among authors: kirschning a. Org Lett. 2021 Apr 16;23(8):3162-3166. doi: 10.1021/acs.orglett.1c00882. Epub 2021 Apr 7. Org Lett. 2021. PMID: 33826848

8

Substrate specificity of α-humulene synthase from Zingiber zerumbet Smith and determination of kinetic constants by a spectrophotometric assay.

Alemdar S, König JC, Seidel K, Kirschning A, Scheper T, Beutel S. Alemdar S, et al. Among authors: kirschning a. Eng Life Sci. 2018 Jul 3;18(9):654-658. doi: 10.1002/elsc.201800019. eCollection 2018 Sep. Eng Life Sci. 2018. PMID: 32624945 Free PMC article.

9

Exploiting the Synthetic Potential of Sesquiterpene Cyclases for Generating Unnatural Terpenoids.

Oberhauser C, Harms V, Seidel K, Schröder B, Ekramzadeh K, Beutel S, Winkler S, Lauterbach L, Dickschat JS, Kirschning A. Oberhauser C, et al. Among authors: kirschning a. Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11802-11806. doi: 10.1002/anie.201805526. Epub 2018 Aug 7. Angew Chem Int Ed Engl. 2018. PMID: 29953712

10

Methyl-Shifted Farnesyldiphosphate Derivatives Are Substrates for Sesquiterpene Cyclases.

Harms V, Schröder B, Oberhauser C, Tran CD, Winkler S, Dräger G, Kirschning A. Harms V, et al. Among authors: kirschning a. Org Lett. 2020 Jun 5;22(11):4360-4365. doi: 10.1021/acs.orglett.0c01345. Epub 2020 May 20. Org Lett. 2020. PMID: 32432889

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