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Page 1
Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation.
Fayed EA, El-Sebaey SA, Ebrahim MA, Abu-Elfotuh K, El-Sayed Mansour R, Mohamed EK, Hamdan AME, Al-Subaie FT, Albalawi GS, Albalawi TM, Hamdan AM, Mohammed AA, Ramsis TM. Fayed EA, et al. Among authors: hamdan ame. Eur J Med Chem. 2024 Dec 24;284:117201. doi: 10.1016/j.ejmech.2024.117201. Online ahead of print. Eur J Med Chem. 2024. PMID: 39731791 Free article.
In silico and in vivo analysis of the relationship between ADHD and social isolation in pups rat model: Implication of redox mechanisms, and the neuroprotective impact of Punicalagin.
Abu-Elfotuh K, Darwish A, Elsanhory HMA, Alharthi HH, Hamdan AME, Hamdan AM, Masoud RAE, Abd El-Rhman RH, Reda E. Abu-Elfotuh K, et al. Among authors: hamdan ame, hamdan am. Life Sci. 2023 Dec 15;335:122252. doi: 10.1016/j.lfs.2023.122252. Epub 2023 Nov 5. Life Sci. 2023. PMID: 37935275 Free article.
The potential anti-Alzheimer's activity of Oxalis corniculata Linn. Methanolic extract in experimental rats: Role of APOE4/LRP1, TLR4/NF-κβ/NLRP3, Wnt 3/β-catenin/GSK-3β, autophagy and apoptotic cues.
Abu-Elfotuh K, Hamdan AME, Mohamed SA, Bakr RO, Ahmed AH, Atwa AM, Hamdan AM, Alanzai AG, Alnahhas RK, Gowifel AMH, Salem MA. Abu-Elfotuh K, et al. Among authors: hamdan ame, hamdan am. J Ethnopharmacol. 2024 Apr 24;324:117731. doi: 10.1016/j.jep.2024.117731. Epub 2024 Jan 11. J Ethnopharmacol. 2024. PMID: 38218505 Free article.
Neuroprotective effects of punicalagin and/or micronized zeolite clinoptilolite on manganese-induced Parkinson's disease in a rat model: Involvement of multiple pathways.
Abu-Elfotuh K, Abbas AN, Najm MAA, Qasim QA, Hamdan AME, Abdelrehim AB, Gowifel AMH, Al-Najjar AH, Atwa AM, Kozman MR, Khalil AS, Negm AM, Mousa SNM, Hamdan AM, Abd El-Rhman RH, Abdelmohsen SR, Tolba AMA, Aboelsoud HA, Salahuddin A, Darwish A. Abu-Elfotuh K, et al. Among authors: hamdan ame. CNS Neurosci Ther. 2024 Oct;30(10):e70008. doi: 10.1111/cns.70008. CNS Neurosci Ther. 2024. PMID: 39374157 Free PMC article.
The consumption pattern and perception of using artificial sweeteners among the public in Tabuk region, Saudi Arabia.
Alharthi SAS, Alaisayi KHA, Alalawi LYS, Alamri ROS, Abu-Elfotuh K, Alenazi TS, Amirthalingam P, Albariqi HAH, Mohammed AA, Alsubayti N, Hamdan AME, Kozman MR. Alharthi SAS, et al. Among authors: hamdan ame. Front Public Health. 2023 Jun 22;11:1166868. doi: 10.3389/fpubh.2023.1166868. eCollection 2023. Front Public Health. 2023. PMID: 37427264 Free PMC article.
Neuroprotective Effect of Morin Hydrate against Attention-Deficit/Hyperactivity Disorder (ADHD) Induced by MSG and/or Protein Malnutrition in Rat Pups: Effect on Oxidative/Monoamines/Inflammatory Balance and Apoptosis.
Salem HA, Elsherbiny N, Alzahrani S, Alshareef HM, Abd Elmageed ZY, Ajwah SM, Hamdan AME, Abdou YS, Galal OO, El Azazy MKA, Abu-Elfotuh K. Salem HA, et al. Among authors: hamdan ame. Pharmaceuticals (Basel). 2022 Aug 17;15(8):1012. doi: 10.3390/ph15081012. Pharmaceuticals (Basel). 2022. PMID: 36015160 Free PMC article.
Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and PERK/CHOP/Bcl-2 Pathways.
Abu-Elfotuh K, Tolba AMA, Hussein FH, Hamdan AME, Rabeh MA, Alshahri SA, Ali AA, Mosaad SM, Mahmoud NA, Elsaeed MY, Abdelglil RM, El-Awady RR, Galal ERM, Kamal MM, Elsisi AMM, Darwish A, Gowifel AMH, Mahran YF. Abu-Elfotuh K, et al. Among authors: hamdan ame. Pharmaceutics. 2023 Jul 31;15(8):2063. doi: 10.3390/pharmaceutics15082063. Pharmaceutics. 2023. PMID: 37631278 Free PMC article.
The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways.
Abu-Elfotuh K, Selim HMRM, Riad OKM, Hamdan AME, Hassanin SO, Sharif AF, Moustafa NM, Gowifel AMH, Mohamed MYA, Atwa AM, Zaghlool SS, El-Din MN. Abu-Elfotuh K, et al. Among authors: hamdan ame. Front Pharmacol. 2023 Aug 2;14:1208252. doi: 10.3389/fphar.2023.1208252. eCollection 2023. Front Pharmacol. 2023. PMID: 37601053 Free PMC article.
Punicalagin's Protective Effects on Parkinson's Progression in Socially Isolated and Socialized Rats: Insights into Multifaceted Pathway.
Salem HA, Abu-Elfotuh K, Alzahrani S, Rizk NI, Ali HS, Elsherbiny N, Aljohani A, Hamdan AME, Chellasamy P, Abdou NS, Gowifel AMH, Darwish A, Ibrahim OM, Abd Elmageed ZY. Salem HA, et al. Among authors: hamdan ame. Pharmaceutics. 2023 Oct 4;15(10):2420. doi: 10.3390/pharmaceutics15102420. Pharmaceutics. 2023. PMID: 37896179 Free PMC article.
28 results