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Pharmacological inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet.
Lee Y, Tassey J, Sarkar A, Levi JN, Lee S, Liu NQ, Drake AC, Nguyen F, Magallanes J, Stevic U, Lu J, Ge D, Tang H, Mkaratigwa T, Yang J, Bian F, Shkhyan R, Bonaguidi MA, Evseenko D. Lee Y, et al. Among authors: evseenko d. Sci Rep. 2024 Dec 28;14(1):31151. doi: 10.1038/s41598-024-82414-7. Sci Rep. 2024. PMID: 39732741 Free PMC article.
Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet.
Lee Y, Sarkar A, Tassey J, Levi JN, Lee S, Liu NQ, Drake AC, Magallanes J, Stevic U, Lu J, Ge D, Tang H, Mkaratigwa T, Bian F, Shkhyan R, Bonaguidi M, Evseenko D. Lee Y, et al. Among authors: evseenko d. bioRxiv [Preprint]. 2024 Apr 11:2024.04.08.588362. doi: 10.1101/2024.04.08.588362. bioRxiv. 2024. Update in: Sci Rep. 2024 Dec 28;14(1):31151. doi: 10.1038/s41598-024-82414-7 PMID: 38645030 Free PMC article. Updated. Preprint.
Repurposing of a gill gene regulatory program for outer ear evolution.
Thiruppathy M, Teubner L, Roberts RR, Lasser M, Moscatello A, Chen YW, Hochstim C, Ruffins S, Sarkar A, Tassey J, Evseenko D, Lozito TP, Willsey HR, Gillis JA, Crump JG. Thiruppathy M, et al. Among authors: evseenko d. Nature. 2025 Jan 9. doi: 10.1038/s41586-024-08577-5. Online ahead of print. Nature. 2025. PMID: 39788155
Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis.
Shkhyan R, Flynn C, Lamoure E, Sarkar A, Van Handel B, Li J, York J, Banks N, Van der Horst R, Liu NQ, Lee S, Bajaj P, Vadivel K, Harn HI, Tassey J, Lozito T, Lieberman JR, Chuong CM, Hurtig MS, Evseenko D. Shkhyan R, et al. Among authors: evseenko d. Sci Transl Med. 2023 Mar 22;15(688):eabq2395. doi: 10.1126/scitranslmed.abq2395. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947594 Free PMC article.
STAT3 promotes a youthful epigenetic state in articular chondrocytes.
Sarkar A, Liu NQ, Magallanes J, Tassey J, Lee S, Shkhyan R, Lee Y, Lu J, Ouyang Y, Tang H, Bian F, Tao L, Segil N, Ernst J, Lyons K, Horvath S, Evseenko D. Sarkar A, et al. Among authors: evseenko d. Aging Cell. 2023 Feb;22(2):e13773. doi: 10.1111/acel.13773. Epub 2023 Jan 13. Aging Cell. 2023. PMID: 36638270 Free PMC article.
A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification.
Magallanes J, Liu NQ, Zhang J, Ouyang Y, Mkaratigwa T, Bian F, Van Handel B, Skorka T, Petrigliano FA, Evseenko D. Magallanes J, et al. Among authors: evseenko d. Front Cell Dev Biol. 2022 Aug 24;10:954028. doi: 10.3389/fcell.2022.954028. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36092701 Free PMC article.
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